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Proteins/UNIPROT:Q9P2S5
The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles..
Function from UniProtKB (Q9P2S5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
21 statements
21 statements · 2 reference databases · Subject: WRAP73 · Sources: gene ontology, Hetionet
3 names
Resolves to: WRAP73