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Proteins/UNIPROT:P78364
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression..
Function from UniProtKB (P78364), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
68 statements
68 statements · 4 reference databases · Subject: PHC1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
4 names
Resolves to: PHC1