Proteins/UNIPROT:P31270

HOXA11

ProteinUNIPROT:P31270

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Function from UniProtKB (P31270), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome has a germline basis in HOXA11DiseaseGenCC HGNC:5101|MONDO:0011555Inferred only
radioulnar synostosis with amegakaryocytic thrombocytopenia 1 has a germline basis in HOXA11DiseaseGenCC HGNC:5101|MONDO:0024558Inferred only

Statements

38 statements

38 statements · 4 reference databases · Subject: HOXA11 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

HOXA11 covaries with CCDC85BProteinHetionet hetionet:covaries:11007-3207Inferred only
HOXA11 covaries with CTDNEP1ProteinHetionet hetionet:covaries:23399-3207Inferred only
HOXA11 covaries with HNRNPA0ProteinHetionet hetionet:covaries:10949-3207Inferred only
HNRNPM covaries with HOXA11ProteinHetionet hetionet:covaries:3207-4670Inferred only
HOXA11 covaries with HOXB4ProteinHetionet hetionet:covaries:3207-3214Inferred only
HOXA11 covaries with HOXC13ProteinHetionet hetionet:covaries:3207-3229Inferred only
HOXA11 covaries with MEGF8ProteinHetionet hetionet:covaries:1954-3207Inferred only
NPDC1 covaries with HOXA11ProteinHetionet hetionet:covaries:3207-56654Inferred only
HOXA11 covaries with NR2F6ProteinHetionet hetionet:covaries:2063-3207Inferred only
TBX2 covaries with HOXA11ProteinHetionet hetionet:covaries:3207-6909Inferred only
HOXA11 covaries with TMEM200BProteinHetionet hetionet:covaries:3207-399474Inferred only
TPBGL covaries with HOXA11ProteinHetionet hetionet:covaries:100507050-3207Inferred only

Show the remaining 26

HOXA11 covaries with TRAPPC5ProteinHetionet hetionet:covaries:126003-3207Inferred only
FOXO1 interacts with HOXA11ProteinHetionet hetionet:interacts:2308-3207Inferred only
HOXA11 interacts with GMNNProteinHetionet hetionet:interacts:3207-51053Inferred only
HOXA11 interacts with MEIS1ProteinHetionet hetionet:interacts:3207-4211Inferred only
HOXA11 interacts with PGBD3ProteinHetionet hetionet:interacts:267004-3207Inferred only
HOXA11 interacts with UBCProteinHetionet hetionet:interacts:3207-7316Inferred only
HOXA11 interacts with YY1ProteinHetionet hetionet:interacts:3207-7528Inferred only
HOXA11 participates in Development of ureteric derived collecting systemPathwayWikiPathways WP5053Inferred only
HOXA11 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
HOXA11 participates in Formation of the ureteric budPathwayReactome R-HSA-9830674Inferred only
HOXA11 participates in GDNF RET signaling axisPathwayWikiPathways WP4830Inferred only
HOXA11 participates in Genes controlling nephrogenesisPathwayWikiPathways WP4823Inferred only
HOXA11 participates in Kidney developmentPathwayReactome R-HSA-9830369Inferred only
HOXA11 regulates positive regulation of cell developmentBiological processgene ontology P31270|GO:0010720Inferred only
HOXA11 regulates positive regulation of chondrocyte differentiationBiological processgene ontology P31270|GO:0032332Inferred only
HOXA11 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology P31270|GO:0045893Inferred only
HOXA11 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology P31270|GO:0006357Inferred only
BTG2 increases the expression of HOXA11ProteinHetionet hetionet:regulates:7832-3207Inferred only
GSDMB increases the expression of HOXA11ProteinHetionet hetionet:regulates:55876-3207Inferred only
IKZF1 increases the expression of HOXA11ProteinHetionet hetionet:regulates:10320-3207Inferred only
MET increases the expression of HOXA11ProteinHetionet hetionet:regulates:4233-3207Inferred only
PARL increases the expression of HOXA11ProteinHetionet hetionet:regulates:55486-3207Inferred only
RTCA decreases the expression of HOXA11ProteinHetionet hetionet:regulates:8634-3207Inferred only
SDHB decreases the expression of HOXA11ProteinHetionet hetionet:regulates:6390-3207Inferred only
SGCB decreases the expression of HOXA11ProteinHetionet hetionet:regulates:6443-3207Inferred only
YKT6 decreases the expression of HOXA11ProteinHetionet hetionet:regulates:10652-3207Inferred only

Other names

3 names

Resolves to: HOXA11

Also called: Homeobox protein Hox-1IHomeobox protein Hox-A11HOX1I

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