Proteins/UNIPROT:Q9UKB3

DNAJC12

ProteinUNIPROT:Q9UKB3

Probable co-chaperone that participates in the proper folding of biopterin-dependent aromatic amino acid hydroxylases, which include phenylalanine-4-hydroxylase (PAH), tyrosine 3-monooxygenase (TH) and peripheral and neuronal tryptophan hydroxylases (TPH1 and TPH2)..

Function from UniProtKB (Q9UKB3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

hyperphenylalaninemia due to DNAJC12 deficiency has a germline basis in DNAJC12DiseaseGenCC HGNC:28908|MONDO:0044304Inferred only

Statements

21 statements

21 statements · 2 reference databases · Subject: DNAJC12 · Sources: Hetionet, WikiPathways

Order

APP interacts with DNAJC12ProteinHetionet hetionet:interacts:351-56521Inferred only
EEF1D interacts with DNAJC12ProteinHetionet hetionet:interacts:1936-56521Inferred only
DNAJC12 participates in Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalaninePathwayWikiPathways WP4156Inferred only
ALDH6A1 decreases the expression of DNAJC12ProteinHetionet hetionet:regulates:4329-56521Inferred only
FADD increases the expression of DNAJC12ProteinHetionet hetionet:regulates:8772-56521Inferred only
DNAJC12 decreases the expression of GOLT1BProteinHetionet hetionet:regulates:56521-51026Inferred only
DNAJC12 decreases the expression of H2BC12ProteinHetionet hetionet:regulates:56521-85236Inferred only
DNAJC12 decreases the expression of KRT18ProteinHetionet hetionet:regulates:56521-3875Inferred only
DNAJC12 decreases the expression of LGALS1ProteinHetionet hetionet:regulates:56521-3956Inferred only
DNAJC12 increases the expression of OXCT1ProteinHetionet hetionet:regulates:56521-5019Inferred only
PHB2 increases the expression of DNAJC12ProteinHetionet hetionet:regulates:11331-56521Inferred only
REL decreases the expression of DNAJC12ProteinHetionet hetionet:regulates:5966-56521Inferred only

Show the remaining 9

DNAJC12 decreases the expression of S100PProteinHetionet hetionet:regulates:56521-6286Inferred only
SF3B1 decreases the expression of DNAJC12ProteinHetionet hetionet:regulates:23451-56521Inferred only
DNAJC12 decreases the expression of SLC35B1ProteinHetionet hetionet:regulates:56521-10237Inferred only
DNAJC12 decreases the expression of SMARCD2ProteinHetionet hetionet:regulates:56521-6603Inferred only
DNAJC12 decreases the expression of TCEA2ProteinHetionet hetionet:regulates:56521-6919Inferred only
DNAJC12 decreases the expression of TMEM50AProteinHetionet hetionet:regulates:56521-23585Inferred only
DNAJC12 decreases the expression of TUBA1AProteinHetionet hetionet:regulates:56521-7846Inferred only
DNAJC12 decreases the expression of USP22ProteinHetionet hetionet:regulates:56521-23326Inferred only
DNAJC12 decreases the expression of VGLL4ProteinHetionet hetionet:regulates:56521-9686Inferred only

Other names

3 names

Resolves to: DNAJC12

Also called: DnaJ homolog subfamily C member 12J domain-containing protein 1JDP1

← Every protein Find it in the graph →