a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

235 compounds within 3 steps: 2 in 1, 25 in 2, 208 in 3

Three steps

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming)
Catalysed by PIGL, PIGW, SLC27A2, SLC27A5endoplasmic reticulumOne of 3 routes
an S-substituted L-cysteineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
3. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
Catalysed by PIGL, ACY3endoplasmic reticulum
D-glucosamine 6-phosphateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
3. D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)
Catalysed by PIGL, AMDHD2, GNPNAT1endoplasmic reticulumOne of 2 routes
5-amino-2-oxopentanoateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. transport of acetate and pyruvate (cytosol to extracellular)
3. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
Catalysed by PIGL, SLC16A4, SLC16A5, SLC16A3 and 3 moreendoplasmic reticulum, extracellular space, cytosol
deoxycholoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)
Catalysed by PIGL, PIGW, SLC27A2, SLC27A5endoplasmic reticulum, cytosolOne of 4 routes
decanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. medium-chain acyl-CoA ligase (decanoic acid)
Catalysed by PIGL, PIGW, ACSM4, ACSM1 and 4 moreendoplasmic reticulum, cytosolOne of 7 routes
(2E)-hexadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Carnitine O-Palmitoyltransferase
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosolOne of 4 routes
(9Z)-hexadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (palmitolate)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 11 routes
(4R)-4-hydroxy-2-oxoglutarateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. transport of acetate and pyruvate (cytosol to extracellular)
3. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by PIGL, SLC16A4, SLC16A5, SLC16A3 and 3 moreendoplasmic reticulum, extracellular space, cytosol
3-hydroxyisovaleryl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)
Catalysed by PIGL, PIGW, CPT1A, CPT1Bendoplasmic reticulum, cytosol
CHEBI:63544Reach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (adrenic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 7 routes
a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
a 1-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
hexacosanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (cerotic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
tetracosanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 10 routes
docosanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 9 routes
a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
a 2-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
2-acetamido-2-deoxy-D-glucopyranose 1-phosphateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
3. phosphoglucomutase (N-acetylglucosamine-6-phosphate)
Catalysed by PIGL, AMDHD2, PGM3endoplasmic reticulum, cytosol
(2E)-octadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Carnitine O-Palmitoyltransferase
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 8 routes
(4S)-4-hydroxy-2-oxoglutarateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. transport of acetate and pyruvate (cytosol to extracellular)
3. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by PIGL, SLC16A4, SLC16A5, SLC16A3 and 3 moreendoplasmic reticulum, extracellular space, cytosol
1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 4 routes
1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 3 routes
1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 3 routes
4-acetamidobutanalReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-acetylputrescine + H2O = putrescine + acetate
3. N-Acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing)
Catalysed by PIGL, HDAC10, AOC2, AOC1 and 3 moreendoplasmic reticulum, cytosolOne of 2 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosolOne of 3 routes
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 8 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 2 routes
1-octadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 5 routes
2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 9 routes