Proteins/UNIPROT:Q6NZ67

MZT2B

ProteinUNIPROT:Q6NZ67

Required for the recruitment and the assembly of the gamma-tubulin ring complex (gTuRC) at the centrosome. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation..

Function from UniProtKB (Q6NZ67), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

49 statements

49 statements · 2 reference databases · Subject: MZT2B · Sources: Hetionet, Reactome

Order

CDC37 interacts with MZT2BProteinHetionet hetionet:interacts:11140-80097Inferred only
IKBKE interacts with MZT2BProteinHetionet hetionet:interacts:80097-9641Inferred only
SETDB1 interacts with MZT2BProteinHetionet hetionet:interacts:80097-9869Inferred only
TUBG1 interacts with MZT2BProteinHetionet hetionet:interacts:7283-80097Inferred only
UBC interacts with MZT2BProteinHetionet hetionet:interacts:7316-80097Inferred only
MZT2B participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
MZT2B participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
MZT2B participates in Centrosome maturationPathwayReactome R-HSA-380287Inferred only
MZT2B participates in G2/M TransitionPathwayReactome R-HSA-69275Inferred only
MZT2B participates in M PhasePathwayReactome R-HSA-68886Inferred only
MZT2B participates in Mitotic G2-G2/M phasesPathwayReactome R-HSA-453274Inferred only
MZT2B participates in Mitotic PrometaphasePathwayReactome R-HSA-68877Inferred only

Show the remaining 37

MZT2B participates in Recruitment of mitotic centrosome proteins and complexesPathwayReactome R-HSA-380270Inferred only
MZT2B participates in Recruitment of NuMA to mitotic centrosomesPathwayReactome R-HSA-380320Inferred only
ADGRE1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:2015-80097Inferred only
ADGRG1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:9289-80097Inferred only
AKAP8L decreases the expression of MZT2BProteinHetionet hetionet:regulates:26993-80097Inferred only
ANO10 decreases the expression of MZT2BProteinHetionet hetionet:regulates:55129-80097Inferred only
ARL1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:400-80097Inferred only
BAMBI increases the expression of MZT2BProteinHetionet hetionet:regulates:25805-80097Inferred only
BLM decreases the expression of MZT2BProteinHetionet hetionet:regulates:641-80097Inferred only
CBR3 decreases the expression of MZT2BProteinHetionet hetionet:regulates:874-80097Inferred only
CENPE decreases the expression of MZT2BProteinHetionet hetionet:regulates:1062-80097Inferred only
CSNK1E decreases the expression of MZT2BProteinHetionet hetionet:regulates:1454-80097Inferred only
CTNNAL1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:8727-80097Inferred only
EBF1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:1879-80097Inferred only
ECSIT decreases the expression of MZT2BProteinHetionet hetionet:regulates:51295-80097Inferred only
ERG decreases the expression of MZT2BProteinHetionet hetionet:regulates:2078-80097Inferred only
EXOSC8 decreases the expression of MZT2BProteinHetionet hetionet:regulates:11340-80097Inferred only
FDPS decreases the expression of MZT2BProteinHetionet hetionet:regulates:2224-80097Inferred only
GLI1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:2735-80097Inferred only
HS2ST1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:9653-80097Inferred only
MRGPRX4 increases the expression of MZT2BProteinHetionet hetionet:regulates:117196-80097Inferred only
P4HA1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:5033-80097Inferred only
PABPC1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:26986-80097Inferred only
PARN decreases the expression of MZT2BProteinHetionet hetionet:regulates:5073-80097Inferred only
PLPP3 decreases the expression of MZT2BProteinHetionet hetionet:regulates:8613-80097Inferred only
POLR2E decreases the expression of MZT2BProteinHetionet hetionet:regulates:5434-80097Inferred only
QRSL1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:55278-80097Inferred only
RAD9A decreases the expression of MZT2BProteinHetionet hetionet:regulates:5883-80097Inferred only
RBPJ decreases the expression of MZT2BProteinHetionet hetionet:regulates:3516-80097Inferred only
RTN2 increases the expression of MZT2BProteinHetionet hetionet:regulates:6253-80097Inferred only
RXRA decreases the expression of MZT2BProteinHetionet hetionet:regulates:6256-80097Inferred only
SOD1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:6647-80097Inferred only
SRSF3 decreases the expression of MZT2BProteinHetionet hetionet:regulates:6428-80097Inferred only
STAT1 decreases the expression of MZT2BProteinHetionet hetionet:regulates:6772-80097Inferred only
WFS1 increases the expression of MZT2BProteinHetionet hetionet:regulates:7466-80097Inferred only
ZNF296 decreases the expression of MZT2BProteinHetionet hetionet:regulates:162979-80097Inferred only
ZNF684 decreases the expression of MZT2BProteinHetionet hetionet:regulates:127396-80097Inferred only

Other names

4 names

Resolves to: MZT2B

Also called: FAM128BMitotic-spindle organizing protein 2BMitotic-spindle organizing protein associated with a ring of gamma-tubulin 2BMOZART2B

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