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Proteins/UNIPROT:Q6P4I2
Component of a multiprotein complex required for the assembly of the RNA endonuclease module of the integrator complex. Associates with INTS9 and INTS11 in the cytoplasm, stabilizing the INTS9-INTS11 heterodimer and blocking the active site of INTS11. BRAT1 then joins the complex and plugs the active site of INTS11, leading to WDR73 release and nuclear import of INTS9 and INTS11..
Function from UniProtKB (Q6P4I2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
28 statements
28 statements · 2 reference databases · Subject: WDR73 · Sources: Hetionet, WikiPathways
2 names
Resolves to: WDR73