a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

444 compounds within 3 steps: 2 in 1, 86 in 2, 356 in 3

Two steps

docosanoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by LPCAT4, PLA2G4COne of 2 routes
a 2,3-saturated aldehydeReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine
Catalysed by LPCAT4, TMEM86A, TMEM86B
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(13Z)-docosenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(11Z)-eicosenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(15Z)-tetracosenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(17Z)-hexacosenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
heptadecanoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(9Z)-heptadecenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
nonadecanoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
a 2,3-diacyl-sn-glycerolReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by LPCAT4, MOGAT2, MOGAT1
1-O-alkyl-3-acylglycerolReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA
Catalysed by LPCAT4, MOGAT2, AWAT2
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
a 1,3-diacyl-sn-glycerolReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA
Catalysed by LPCAT4, MOGAT1One of 2 routes
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPCAT4, LPCAT2, LPCAT1
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4, MBOAT1, MBOAT2
1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4, LPCAT3One of 2 routes
1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4
1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4
1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4One of 2 routes
1-O-(1Z-alkenyl)-2-acetyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z-alkenyl)-2-acetyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine
Catalysed by LPCAT4, PAFAH2
(5Z)-tetradecenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
an N(2)-acyl-L-glutamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by LPCAT4, GLYATL1B, GLYATL1
(7Z)-hexadecenoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
tricosanoyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. acyl-CoA pool formation and breakdown
Catalysed by LPCAT4cytosol
a 3-oxoacyl-CoAReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
Catalysed by LPCAT4, ACAA1, SCP2, ACAA2 and 1 more

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine

Two steps

Three steps