(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

187 compounds within 3 steps: 1 in 1, 7 in 2, 179 in 3

Three steps

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)
Catalysed by TECRL, TECR, FADS1, GLYATL2cytosol
decanoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. medium-chain acyl-CoA ligase (decanoic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 9 morecytosolOne of 7 routes
(2E)-hexadecenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. Carnitine O-Palmitoyltransferase
Catalysed by TECRL, TECR, ACOT7, BAAT and 6 morecytosolOne of 4 routes
(9Z)-hexadecenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (palmitolate)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 12 routes
a cardiolipinReach from here →
1. very-long-chain enoyl-CoA reductase
2. acyl-CoA pool formation and breakdown
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA = a cardiolipin + CoA
Catalysed by TECRL, TECR, HADHAcytosol
3-hydroxyisovaleryl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)
Catalysed by TECRL, TECR, ACOT7, BAAT and 5 morecytosol
an all-trans-retinyl esterReach from here →
1. very-long-chain enoyl-CoA reductase
2. acyl-CoA pool formation and breakdown
3. all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA
Catalysed by TECRL, TECR, DGAT1, PNPLA4 and 2 morecytosol
CHEBI:63544Reach from here →
1. very-long-chain enoyl-CoA reductase
2. fatty acyl-CoA desaturase (N-C20:3CoA -> N-C20:4CoA)
3. fatty-acyl-CoA elongation (N-C20:4CoA)
Catalysed by TECRL, TECR, FADS1, ELOVL4 and 3 morecytosolOne of 9 routes
a 1,2-diacyl-sn-glycero-3-phosphoethanolamineReach from here →
1. very-long-chain enoyl-CoA reductase
2. acyl-CoA pool formation and breakdown
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECRL, TECR, LPCAT4, LPCAT3 and 2 morecytosol
a triacyl-sn-glycerolReach from here →
1. very-long-chain enoyl-CoA reductase
2. acyl-CoA pool formation and breakdown
3. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
Catalysed by TECRL, TECR, DGAT1, MOGAT2 and 4 morecytosol
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. very-long-chain enoyl-CoA reductase
2. acyl-CoA pool formation and breakdown
3. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by TECRL, TECR, LCLAT1, LPCAT1 and 1 morecytosol
hexacosanoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (cerotic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 6 routes
tetracosanoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 11 routes
docosanoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 10 routes
(2E)-octadecenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. Carnitine O-Palmitoyltransferase
Catalysed by TECRL, TECR, ACOT7, BAAT and 6 morecytosolOne of 3 routes
3-oxo-(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Beta Oxidation of Fatty Acid
3. (6Z,9Z,12Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z)-eicosatrienoyl-CoA + CO2 + CoA
Catalysed by TECRL, TECR, ACADM, ACADS and 2 morecytosol, mitochondrial matrix
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 9 routes
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositolReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA
Catalysed by TECRL, TECR, FADS1, LCLAT1cytosol
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by TECRL, TECR, FADS1, AGPAT2 and 1 morecytosol
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3 and 1 morecytosol
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
(7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + malonyl-CoA + H(+) = (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + CoA
Catalysed by TECRL, TECR, FADS1, ELOVL7 and 2 morecytosol
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 10 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 7 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 8 routes
(13Z)-docosenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 7 routes
(11Z)-eicosenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 8 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 6 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 5 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 7 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 6 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 8 routes
heptadecanoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 7 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 6 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 6 routes
1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3 and 2 morecytosol
1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3 and 2 morecytosol
1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphateReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA
Catalysed by TECRL, TECR, FADS1, GPAT2 and 5 morecytosol
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. very-long-chain enoyl-CoA reductase
2. fatty acyl-CoA desaturase (N-C20:3CoA -> N-C20:4CoA)
3. glycerol-3-phosphate 1-O-acyltransferase (arachidonyl-CoA)
Catalysed by TECRL, TECR, FADS1, GPAT3 and 3 morecytosolOne of 2 routes
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-dodecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-dodecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-dodecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-eicosanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT3cytosol
1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. very-long-chain enoyl-CoA reductase
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECRL, TECR, FADS1, LPCAT4 and 1 morecytosol
nonadecanoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by TECRL, TECR, ACOT7, BAAT and 11 morecytosolOne of 7 routes
(11Z)-octadecenoyl-CoAReach from here →
1. very-long-chain enoyl-CoA reductase
2. Dihomo-gamma-linolenoyl-CoA hydrolase
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by TECRL, TECR, ACOT7, BAAT and 6 morecytosolOne of 3 routes