1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

297 compounds within 3 steps: 4 in 1, 76 in 2, 217 in 3

One step

Two steps

(S)-carnitineReach from here →
1. 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-acyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
2. Utilized Transport
Catalysed by PLA2G15, PNPLA8endoplasmic reticulum, cytosolOne of 2 routes
AReach from here →
1. 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-acyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = prostaglandin H2 + A + H2O
Catalysed by PLA2G15, PNPLA8, PTGS1, PTGS2

One of 3 routes

(14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 6 more

(14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 6 more

(11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP2C8, CYP2C9 and 3 more

(11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP2C8 and 5 more

(8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP2C9, CYP2J2

(8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP2D6 and 4 more

5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 24 morecytosolOne of 4 routes

17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 24 morecytosolOne of 2 routes

16-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1

10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP3A4, CYP2C9

(8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX15

(14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX15

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by PLA2G15, PNPLA8, SLCO1B1extracellular space, cytosolOne of 2 routes

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanineReach from here →

Catalysed by PLA2G15, PNPLA8, PM20D1

7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 24 morecytosolOne of 2 routes

13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 24 morecytosolOne of 2 routes

13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP2C9

a 3-(acyloxy)acyl derivative of bacterial toxinReach from here →

Catalysed by DDHD1, AOAH

16(R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, CYP1A1, CYP1A2 and 24 morecytosol

2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by DDHD1, PTGS2

sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PLA2G15, PNPLA8, ASPG

8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8cytosolOne of 2 routes

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serineReach from here →

Catalysed by PLA2G15, PNPLA8, FAAH, PM20D1

arachidonoyl-CoAReach from here →

Catalysed by PLA2G15, PNPLA8, SLC27A2, ACSL4 and 6 morecytosolOne of 3 routes

12(S)-HPETEReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX12cytosolOne of 4 routes

15(S)-HPETEReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX15B, ALOX15cytosolOne of 4 routes

5(S)-HPETEReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX5cytosol

CHEBI:16856Reach from here →

Catalysed by PLA2G15, PNPLA8extracellular space, cytosolOne of 2 routes

sn-glycerol 3-phosphocholineReach from here →

Catalysed by PLA2G15, PNPLA8, ASPG

a monoacylglycerolReach from here →

Catalysed by DDHD1, LIPE

O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronateReach from here →

Catalysed by PLA2G15, PNPLA8, UGT1A9, UGT2B7 and 4 more

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →

Catalysed by PLA2G15, PNPLA8, FAAHcytosol

fatty acidReach from here →

Catalysed by PLA2G15, PNPLA8cytosolOne of 4 routes

a fatty aldehydeReach from here →

Catalysed by DDHD1, ALDH3A2

2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerolReach from here →

Catalysed by PLA2G15, PNPLA8, FAAHcytosol

(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →

Catalysed by PLA2G15, PNPLA8, SLC27A2, ACSL4 and 9 more

prostaglandin H2Reach from here →

Catalysed by PLA2G15, PNPLA8, PTGS1, PTGS2cytosolOne of 3 routes

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX5, ALOX15 and 1 more

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX15B, ALOX15 and 1 more

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G15, PNPLA8, ALOX5

leukotriene A4Reach from here →

Catalysed by PLA2G15, PNPLA8, ALOX5

ethanolamineReach from here →

Catalysed by PLA2G15, PNPLA8, ENPP2

a 1-acyl-sn-glycero-3-phosphateReach from here →

Catalysed by PLA2G15, PNPLA8, ENPP2

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →

Catalysed by PLA2G15, PNPLA8, FAAH, PM20D1