What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
7 statements
7 statements · 1 reference database · Subject: (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA · Sources: Human-GEM
- (8Z,11Z,14Z)-eicosatrienoyl-CoA is converted to (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoACompoundHuman-GEM MAR03448Inferred only
- (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA is converted to (8Z,11Z,14Z)-eicosatrienoyl-CoACompoundHuman-GEM MAR03394Inferred only
- (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA is converted to (8Z,11Z,14Z)-eicosatrienoyl-CoACompoundHuman-GEM MAR02378Inferred only
- (8Z,11Z,14Z)-eicosatrienoyl-CoA is converted to (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoACompoundHuman-GEM MAR03394Inferred only
- (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA is a substrate of ELOVL1ProteinHuman-GEM MAR03394Inferred only
- (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA is a substrate of TECRProteinHuman-GEM MAR02378Inferred only
- (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA is a substrate of TECRLProteinHuman-GEM MAR02378Inferred only
Reactions
11 reactions
MAM00710cwater+(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR02376CC BY 4.0Reference data
proton+NADPH(4-)+(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA(8Z,11Z,14Z)-eicosatrienoyl-CoA+NADP(3-)
Reaction pageLeft to rightBalancedEC 1.3.1.93GO:0005829
Human-GEM MAR02378CC BY 4.0Reference data
proton+NADPH(4-)+(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA(8Z,11Z,14Z)-eicosatrienoyl-CoA+NADP(3-)
Catalysed by ELOVL1
Reaction pageReversibleBalancedEC 3.3.2.9GO:0005783
Human-GEM MAR03394CC BY 4.0Reference data
MAM03034m(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA
Catalysed by ECH1 or ECI1 or ECI2
Reaction pageLeft to rightBalancedEC 5.3.3.8, 5.3.3.-GO:0005759
Human-GEM MAR03447CC BY 4.0Reference data
(8Z,11Z,14Z)-eicosatrienoyl-CoA+FADFADH2+(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA
Catalysed by ACADVL or ACADL or ACADM or ACAD9
Reaction pageLeft to rightBalancedEC 1.3.8.7, 1.3.8.8, 1.3.8.9, 1.3.99.-GO:0005759
Human-GEM MAR03448CC BY 4.0Reference data
water+(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAMAM00710m
Catalysed by HADHA
Reaction pageLeft to rightBalancedEC 4.2.1.17GO:0005759
Human-GEM MAR03449CC BY 4.0Reference data
MAM03034x(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA
Catalysed by ECI2 & HADHA & ECI1 & EHHADH
Reaction pageLeft to rightBalancedEC 5.3.3.8GO:0005777
Human-GEM MAR03462CC BY 4.0Reference data
water+(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAMAM00710x
Catalysed by ECI2 & HADHA & ECI1 & EHHADH
Reaction pageLeft to rightBalancedEC 4.2.1.17GO:0005777
Human-GEM MAR03463CC BY 4.0Reference data
CHEBI:76411(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA+water
Catalysed by HSD17B4
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:39315CC BY 4.0Reference data
(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA+NADPH(4-)+hydron(8Z,11Z,14Z)-eicosatrienoyl-CoA+NADP(3-)
Catalysed by TECR
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:39319CC BY 4.0Reference data
CHEBI:233777(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:84855CC BY 4.0Reference data