Compound
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine
A phosphatidylethanolamine 36:4 zwitterion obtained by transfer of a proton from the phosphate to the amino group of 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine.
Definition from ChEBI (CHEBI:73009), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C41H74NO8P
- Mass
- 740.016 g/mol
- Charge
- 0
- InChIKey
- DRIVXEVMDWCWLI-CAQMIEAISA-N
- SMILES
- CCCCC/C=CC/C=CC/C=CC/C=CCCCC(=O)O[C@H](COC(=O)CCCCCCCCCCCCCCC)COP(=O)([O-])OCC[NH3+]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
16 entities
16 entities reached.
0 reported hops16 assembled from the scaffold
- PLTPProteinUNIPROT:P55058transported byInferred only44 paths44 endpoints
- PLA2G2AProteinUNIPROT:P14555substrate ofInferred only37 paths37 endpoints
- PLA2G6ProteinUNIPROT:O60733substrate ofInferred only23 paths23 endpoints
- PLAAT3ProteinUNIPROT:P53816substrate ofInferred only22 paths11 endpoints
- PLA2G4BProteinUNIPROT:P0C869substrate ofInferred only20 paths20 endpoints
- PLA2G5ProteinUNIPROT:P39877substrate ofInferred only17 paths17 endpoints
- PLA2G4DProteinUNIPROT:Q86XP0substrate ofInferred only14 paths14 endpoints
- PLA2G4FProteinUNIPROT:Q68DD2substrate ofInferred only13 paths13 endpoints
- PLAAT4ProteinUNIPROT:Q9UL19substrate ofInferred only13 paths13 endpoints
- PLA2G2FProteinUNIPROT:Q9BZM2substrate ofInferred only11 paths11 endpoints
- PLA2G2EProteinUNIPROT:Q9NZK7substrate ofInferred only11 paths11 endpoints
- PLA2G15ProteinUNIPROT:Q8NCC3substrate ofInferred only10 paths5 endpoints
Show the remaining 4
What the reference databases state
Statements
20 statements
20 statements · 1 reference database · Subject: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine · Sources: Rhea
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:38843Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:38839Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2AProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2EProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2FProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G3ProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4BProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4DProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4FProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G5ProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G6ProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT1ProteinRhea RHEA:40431Inferred only
Show the remaining 8
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT1ProteinRhea RHEA:41348Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT2ProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT2ProteinRhea RHEA:41348Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT3ProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT3ProteinRhea RHEA:41348Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT4ProteinRhea RHEA:41348Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is a substrate of PNPLA8ProteinRhea RHEA:40431Inferred only
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine is transported by PLTPProteinRhea RHEA:46492Inferred only
Reactions
6 reactions
1-hexadecanoyl-sn-glycero-3-phosphoethanolamine+(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine+coenzyme A(4-)
Catalysed by LPCAT3
Reaction pageLeft to rightBalanced
Rhea RHEA:36023CC BY 4.0Reference data
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine+N-(acetyl)-sphing-4-enine1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine+1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by PLA2G15
Reaction pageLeft to rightBalanced
Rhea RHEA:38839CC BY 4.0Reference data
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine+N-(acetyl)-sphing-4-enine2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine+1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PLA2G15
Reaction pageLeft to rightBalanced
Rhea RHEA:38843CC BY 4.0Reference data
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine+water1-hexadecanoyl-sn-glycero-3-phosphoethanolamine+(5Z,8Z,11Z,14Z)-eicosatetraenoate+hydron
Catalysed by PLA2G6 or PLA2G4B or PLA2G2A or PLA2G5 or PLAAT3 or PLA2G4F or PLA2G4D or PLA2G2F or PLAAT1 or PNPLA8 or PLAAT2 or PLA2G3 and 1 more alternative
Reaction pageLeft to rightBalanced
Rhea RHEA:40431CC BY 4.0Reference data
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine+water2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine+hexadecanoate+hydron
Catalysed by PLAAT3 or PLAAT1 or PLAAT2 or PLAAT4
Reaction pageLeft to rightBalanced
Rhea RHEA:41348CC BY 4.0Reference data
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine
Transported by PLTP
Reaction pageLeft to rightBalanced
Rhea RHEA:46492CC BY 4.0Reference data
Where it reaches
9 systems, 16 regions, 43 tissues, 43 transporter routes — routes, not measurements: transporters known to carry 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine are expressed there, and no source reports it arriving.
Loading the model…
Other names
10 names
Resolves to: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine
- Also called
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine zwitterion1-hexadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion1-palmitoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine zwitterion1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4) zwitterion1-palmitoyl-2-arachidonoyl-GPE zwitterion1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterionGPE(16:0/20:4) zwitterionPE(16:0/20:4(5Z,8Z,11Z,14Z))PE(16:0/20:4(5Z,8Z,11Z,14Z)) zwitterion
- Systematic name
- 2-azaniumylethyl (2R)-3-(hexadecanoyloxy)-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy]propyl phosphate