(2E)-octadecenoyl-CoA

1. Carnitine O-Palmitoyltransferase
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal

Catalysed by CPT1A, CPT1C, CPT1B, ACAA1 and 3 morecytosol, peroxisome

1. Carnitine O-Palmitoyltransferase
2. Production of Hexadecanedioylcarnitine

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 2 routes

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA

Catalysed by FADS2, AGPAT4cytosol

1. Carnitine O-Palmitoyltransferase
2. fatty-acid-CoA ligase

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2cytosolOne of 2 routes

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by TECRL, TECR, LPCAT4cytosol

1. Carnitine O-Palmitoyltransferase
2. medium-chain acyl-CoA ligase (undecylic acid)

Catalysed by CPT1A, CPT1C, CPT1B, ACSM4 and 5 morecytosolOne of 3 routes

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

Catalysed by FADS2, ACADL, ACADVL, ACAD9cytosol

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. Acyl-CoA:cholesterol O-acyltransferase

Catalysed by TECRL, TECR, SOAT2, SOAT1cytosol, endoplasmic reticulumOne of 2 routes

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. hexadecasphinganine + octadecanoyl-CoA = N-octadecanoylhexadecasphinganine + CoA + H(+)

Catalysed by TECRL, TECR, CERS1, CERS4cytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA

Catalysed by FADS2, HADHAcytosol

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA

Catalysed by TECRL, TECR, LCLAT1cytosol

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. (R)-carnitine + octadecanoyl-CoA = O-octadecanoyl-(R)-carnitine + CoA

Catalysed by TECRL, TECR, CPT2cytosol

1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (physeteric acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 8 routes

1. Carnitine O-Palmitoyltransferase
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial

Catalysed by CPT1A, CPT1C, CPT1B, ACADM and 3 morecytosol, mitochondrial matrix

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA

Catalysed by TECRL, TECR, LPGAT1cytosol

1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA

Catalysed by TECRL, TECR, LPGAT1cytosol

1. Carnitine O-Palmitoyltransferase
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)

Catalysed by CPT1A, CPT1C, CPT1B, HADHA and 2 morecytosol, mitochondrial matrix

1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 8 routes

1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 4 routes

1. Carnitine O-Palmitoyltransferase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine

Catalysed by CPT1A, CPT1C, CPT1B, GLYAT and 3 morecytosol, mitochondrial matrixOne of 2 routes

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. Acyl-CoA:cholesterol O-acyltransferase
3. Steryl-ester acylhydrolase