Compound

11-hydroxy-(9Z,12Z)-octadecadienoate

A HODE(1−) that is the conjugate base of (9Z,12Z)-11-hydroxyoctadecadienoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.

Definition from ChEBI (CHEBI:136522), read 2026-09-23. CC BY 4.0.

CHEBI:136522ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of 11-hydroxy-(9Z,12Z)-octadecadienoate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C18H31O3
Mass: 295.443 g/mol
Charge: -1
InChIKey: GIJZWHLTBMCTJV-GFCQZRJLSA-M
SMILES: CCCCC/C=CC(O)/C=CCCCCCCCC(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Chemical structure

11-hydroxy-(9Z,12Z)-octadecadienoate has the functional parent (9Z,12Z)-octadecadienoateCompoundChEBI CHEBI:136522Inferred only

Statements

2 statements

2 statements · 1 reference database · Subject: 11-hydroxy-(9Z,12Z)-octadecadienoate · Sources: Rhea

Order

11-hydroxy-(9Z,12Z)-octadecadienoate is metabolised by CYP1A2ProteinRhea RHEA:52284Inferred only
11-hydroxy-(9Z,12Z)-octadecadienoate is metabolised by CYP3A4ProteinRhea RHEA:52284Inferred only

Reactions

1 reaction

(9Z,12Z)-octadecadienoate+reduced [NADPH--hemoprotein reductase]+dioxygen11-hydroxy-(9Z,12Z)-octadecadienoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP1A2 or CYP3A4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:52284CC BY 4.0Reference data

Other names

3 names

Resolves to: 11-hydroxy-(9Z,12Z)-octadecadienoate

Also called: 11-HODE(1-)11-HODE(1−)
Systematic name: (9Z,12Z)-11-hydroxyoctadeca-9,12-dienoate