(2E)-hexadecenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

664 compounds within 3 steps: 4 in 1, 182 in 2, 478 in 3

Two steps

docosanoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 9 routes
N-hexadecanoyl-(4R)-hydroxysphinganineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. (4R)-hydroxysphinganine + hexadecanoyl-CoA = N-hexadecanoyl-(4R)-hydroxysphinganine + CoA + H(+)
Catalysed by TECR, CERS6, CERS5
N-hexadecanoylsphinganineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. sphinganine + hexadecanoyl-CoA = N-hexadecanoylsphinganine + CoA + H(+)
Catalysed by TECR, CERS6, CERS5, CERS2
3-oxooctadecanoyl-CoAReach from here →
1. trans-hexadec-2-enoyl-CoA reductase
2. very-long-chain 3-oxoacyl-CoA synthase (malonyl-CoA)
Catalysed by MECR, ELOVL7, ELOVL1, ELOVL4 and 4 moremitochondrial matrix, cytosolOne of 3 routes
(2E)-octadecenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Carnitine O-Palmitoyltransferase
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 8 routes
1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT1
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by TECR, LCLAT1, LPCAT1, LPGAT1
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by TECR, LPGAT1
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by TECR, LPGAT1
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by TECR, LPGAT1
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by TECR, LCLAT1
1,2-dihexadecanoyl-sn-glycero-3-phosphateReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by TECR, AGPAT2
N-hexadecanoylsphing-4-enineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. sphing-4-enine + hexadecanoyl-CoA = N-hexadecanoylsphing-4-enine + CoA + H(+)
Catalysed by TECR, CERS6, TLCD3B, CERS5 and 1 more
1,2-dihexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, PRDX6, LPCAT3, LPCAT1
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPGAT1
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECR, LPGAT1
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 4 routes
2-hydroxyhexadecanoyl-CoAReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. hexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexadecanoyl-CoA + succinate + CO2
Catalysed by TECR, PHYH
(15Z)-tetracosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(6Z)-hexadecenoyl-CoAReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by TECR, FADS2
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by TECR, AGPAT2, GPAT3, LCLAT1 and 4 more
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT3, LPCAT1
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA
Catalysed by TECR, MBOAT2
1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-dodecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT3, LPCAT1
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT3, LPCAT1
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by TECR, LPGAT1
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-tetradecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT3, LPCAT1
nonadecanoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 3 routes
1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by TECR, LCLAT1
1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Beta Oxidation Fatty Acid
2. octanoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ACADM, ACADS, LPCAT4mitochondrial matrix
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECR, LPCAT4
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. a 1-acyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT4, LPCAT1
1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by TECR, LPCAT1
1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT1
1-eicosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)
2. 1-eicosanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-eicosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by TECR, LPCAT1