beta-D-fructose 6-phosphate

Three steps

• (2R)-2-phosphoglycerateReach from here →
  1. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
  2. alpha-D-glucose 6-phosphate + (2R)-3-phospho-glyceroyl phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)
  3. D-phosphoglycerate 2,3-phosphomutase

  Catalysed by GPI, PGM2L1, BPGM, PGAM2 and 2 morecytosolOne of 2 routes

• 1-hexadecanoylglycerone 3-phosphateReach from here →
  1. beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate
  2. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate
  3. dihydroxyacetone phosphate + hexadecanoyl-CoA = 1-hexadecanoylglycerone 3-phosphate + CoA

  Catalysed by FBP2, FBP1, ALDOA, ALDOB and 2 moreOne of 2 routes

• alpha-D-galactose 1-phosphateReach from here →
  1. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
  2. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
  3. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose

  Catalysed by GPI, PGM1, PGM2, GALT

• an acyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. acyl-CoA:sphingosine N-acyltransferase

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, ASAH1 and 3 morecytosol, Golgi apparatusOne of 2 routes

• (3Z)-dodecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxomyrist-5-enoyl-CoA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, HADHA and 2 morecytosol, mitochondrial matrixOne of 3 routes

• (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 1 morecytosol, endoplasmic reticulumOne of 3 routes

• D-glucosamine 6-phosphateReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1cytosolOne of 2 routes

• deoxycholoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 1 morecytosolOne of 4 routes

• UDP-alpha-D-glucoseReach from here →
  1. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
  2. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
  3. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose

  Catalysed by GPI, PGM1, PGM2, GALTOne of 2 routes

• decanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. medium-chain acyl-CoA ligase (decanoic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, ACSM4 and 5 morecytosolOne of 7 routes

• (2E)-hexadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Carnitine O-Palmitoyltransferase

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosolOne of 4 routes

• (9Z)-hexadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (palmitolate)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 11 routes

• GDP-alpha-D-glucoseReach from here →
  1. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
  2. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
  3. GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP + H(+)

  Catalysed by GPI, PGM1, PGM2, GDPGP1

• 3-hydroxyisovaleryl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 1 morecytosol

• CHEBI:63544Reach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (adrenic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes

• hexacosanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (cerotic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• tetracosanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (lignocerate)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 10 routes

• docosanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (behenic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 9 routes

• alpha-D-ribose 1,5-bisphosphateReach from here →
  1. D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate
  2. D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)
  3. (2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate = alpha-D-ribose 1,5-bisphosphate + (2R)-3-phosphoglycerate + H(+)

  Catalysed by TALDO1, GAPDHS, GAPDH, PGM2L1

• 2-acetamido-2-deoxy-D-glucopyranose 1-phosphateReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. phosphoglucomutase (N-acetylglucosamine-6-phosphate)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, PGM3cytosol

• (2E)-octadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Carnitine O-Palmitoyltransferase

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosolOne of 3 routes

• (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (stearidonic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 8 routes

• D-ribulose 1-phosphateReach from here →
  1. beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate
  2. Glycerone phosphate phosphohydrolase
  3. L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming)

  Catalysed by DCPH1, ALPL, ALPP, ALPI and 4 moreextracellular space, cytosol

• (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (EPA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 9 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (DPA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes

• (9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (linolenate)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes

• (13Z)-docosenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes

• (11Z)-eicosenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes

• (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 4 routes

• (15Z)-tetracosenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (nervonic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes

• (17Z)-hexacosenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (ximenic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 4 routes

• (8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (DHA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes

• heptadecanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (margaric acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes

• (9Z)-heptadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• (11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• nonadecanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes

• (11Z)-octadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosolOne of 3 routes

• dodecanedioyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Activation of dodecanedioic acid

  Catalysed by GNPDA1, GNPDA2, GNPNAT1cytosolOne of 4 routes

• decanedioyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Production of Sebacoylcarnitine

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosolOne of 4 routes

• octanedioyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Production of Suberylcarnitine

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosolOne of 4 routes

• hexanedioyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Activation of adipic acid for Formation of Adipoyl Carnitine

  Catalysed by GNPDA1, GNPDA2, GNPNAT1cytosolOne of 4 routes

• (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes

• (11Z,14Z)-eicosadienoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• (R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Production of 3-Hydroxyoctadecenoylcarnitinec

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosol

• (13Z)-eicosenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes

• 4,8-dimethylnonanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CRAT and 1 morecytosol, peroxisomeOne of 3 routes

• tetradecanedioyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, ACAA1 and 3 morecytosol, peroxisome