Proteins/UNIPROT:Q9P2N7

KLHL13

ProteinUNIPROT:Q9P2N7

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis..

Function from UniProtKB (Q9P2N7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

19 statements

19 statements · 3 reference databases · Subject: KLHL13 · Sources: gene ontology, Hetionet, Reactome

Order

KLHL13 covaries with LRIF1ProteinHetionet hetionet:covaries:55791-90293Inferred only
PDYN covaries with KLHL13ProteinHetionet hetionet:covaries:5173-90293Inferred only
KLHL13 covaries with PGRMC2ProteinHetionet hetionet:covaries:10424-90293Inferred only
KLHL13 covaries with PTPRSProteinHetionet hetionet:covaries:5802-90293Inferred only
KLHL13 covaries with SCARF2ProteinHetionet hetionet:covaries:90293-91179Inferred only
KLHL13 covaries with TMEM59LProteinHetionet hetionet:covaries:25789-90293Inferred only
KLHL13 covaries with TSNAXProteinHetionet hetionet:covaries:7257-90293Inferred only
KLHL13 covaries with WSB2ProteinHetionet hetionet:covaries:55884-90293Inferred only
KLHL13 covaries with ZNF197ProteinHetionet hetionet:covaries:10168-90293Inferred only
KLHL13 covaries with ZNF26ProteinHetionet hetionet:covaries:7574-90293Inferred only
HSP90AB1 interacts with KLHL13ProteinHetionet hetionet:interacts:3326-90293Inferred only
KLHL13 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only

Show the remaining 7

KLHL13 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
KLHL13 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
KLHL13 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
KLHL13 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
KLHL13 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
KLHL13 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
KLHL13 regulates regulation of cytokinesisBiological processgene ontology Q9P2N7|GO:0032465Inferred only

Other names

4 names

Resolves to: KLHL13

Also called: BKLHD2BTB and kelch domain-containing protein 2Kelch-like protein 13KIAA1309

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