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Proteins/UNIPROT:P51693
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I..
The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis..
Function from UniProtKB (P51693), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
99 statements
99 statements · 2 reference databases · Subject: APLP1 · Sources: gene ontology, Hetionet
5 names
Resolves to: APLP1