sphinganine

1. a fatty acyl-CoA + sphinganine = an N-acylsphinganine + CoA + H(+)

Catalysed by CERS1, CERS6, CERS5, CERS4

1. 2-hydroxytetracosanoyl-CoA + sphinganine = N-(2-hydroxytetracosanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS3, CERS2

1. tetracosanoyl-CoA + sphinganine = N-tetracosanoylsphinganine + CoA + H(+)

Catalysed by CERS3, CERS2, CERS4

1. hexacosanoyl-CoA + sphinganine = N-hexacosanoylsphinganine + CoA + H(+)

Catalysed by CERS3, CERS2, CERS4

1. sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)

Catalysed by SPHK2, SPHK1

1. docosanoyl-CoA + sphinganine = N-docosanoylsphinganine + CoA + H(+)

Catalysed by CERS3, CERS2, CERS4

1. 2-hydroxydocosanoyl-CoA + sphinganine = N-(2-hydroxydocosanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS3, CERS2

1. eicosanoyl-CoA + sphinganine = N-eicosanoylsphinganine + CoA + H(+)

Catalysed by CERS1, CERS2, CERS4

1. sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS1, CERS6, CERS3, CERS5 and 2 more

1. 2-hydroxyoctadecanoyl-CoA + sphinganine = N-(2-hydroxyoctadecanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS1, CERS3

1. sphinganine + hexadecanoyl-CoA = N-hexadecanoylsphinganine + CoA + H(+)

Catalysed by CERS6, CERS5, CERS2

1. 2-hydroxyhexadecanoyl-CoA + sphinganine = N-(2-hydroxyhexadecanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS5

1. sphinganine + tetradecanoyl-CoA = N-(tetradecanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS6, CERS5

1. octacosanoyl-CoA + sphinganine = N-(octacosanoyl)-sphinganine + CoA + H(+)

Catalysed by CERS3

1. sphinganine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-sphinganine + CoA + H(+)

Catalysed by CERS5, CERS2

1. (15Z)-tetracosenoyl-CoA + sphinganine = N-(15Z-tetracosenoyl)-sphinganine + CoA + H(+)

Catalysed by CERS2

1. tetracosenoyl-CoA + sphinganine = an N-tetracosenoylsphinganine + CoA + H(+)

Catalysed by CERS2

1. hexacosenoyl-CoA + sphinganine = N-hexacosenoylsphinganine + CoA + H(+)

Catalysed by CERS2

1. 2-hydroxytetracosenoyl-CoA + sphinganine = N-(2-hydroxytetracosenoyl)-sphinganine + CoA + H(+)

Catalysed by CERS2

1. N-(dodecanoyl)-sphinganine + H2O = dodecanoate + sphinganine

Catalysed by ASAH1

1. sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)
2. 3-sn-phosphatidate phosphohydrolase

Catalysed by SPHK2, SPHK1, PLPP1, PLPP3 and 1 morecytosolOne of 5 routes

1. sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)
2. Sphinganine-1-phosphate pamlmitaldehyde-lyase

Catalysed by SPHK2, SPHK1, SGPL1endoplasmic reticulum

1. sphinganine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-sphinganine + CoA + H(+)
2. H2O[r] + N-(9Z-octadecenoyl)-sphinganine[r] = oleate[r] + sphinganine[r]
3. Utilized Transport

Catalysed by CERS5, CERS2, ACER3endoplasmic reticulum, cytosolOne of 2 routes

1. sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)
2. 3-sn-phosphatidate phosphohydrolase
3. sphingosine N-acyltransferase (sphinganine)

Catalysed by and 7 more