Compound
sphinganine
A cationic sphingoid obtained by protonation of the amino group of sphinganine.
Definition from ChEBI (CHEBI:57817), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, cation
- Formula
- C18H40NO2
- Mass
- 302.523 g/mol
- Charge
- +1
- InChIKey
- OTKJDMGTUTTYMP-ZWKOTPCHSA-O
- SMILES
- CCCCCCCCCCCCCCC[C@@H](O)[C@@H]([NH3+])CO
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
9 entities
9 entities reached.
0 reported hops9 assembled from the scaffold
- CERS3ProteinUNIPROT:Q8IU89substrate ofInferred only72 paths9 endpoints
- CERS5ProteinUNIPROT:Q8N5B7substrate ofInferred only42 paths7 endpoints
- CERS1ProteinUNIPROT:P27544substrate ofInferred only32 paths8 endpoints
- CERS6ProteinUNIPROT:Q6ZMG9substrate ofInferred only32 paths8 endpoints
- SPHK1ProteinUNIPROT:Q9NYA1substrate ofInferred only31 paths31 endpoints
- CERS4ProteinUNIPROT:Q9HA82substrate ofInferred only30 paths9 endpoints
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only19 paths19 endpoints
- CERS2ProteinUNIPROT:Q96G23substrate ofInferred only14 paths2 endpoints
- SPHK2ProteinUNIPROT:Q9NRA0substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
47 statements
47 statements · 1 reference database · Subject: sphinganine · Sources: Rhea
- 3-oxosphinganine is converted to sphinganineCompoundRhea RHEA:22640Inferred only
- sphinganine 1-phosphate is converted to sphinganineCompoundRhea RHEA:27514Inferred only
- sphinganine is converted to sphinganine 1-phosphateCompoundRhea RHEA:15465Inferred only
- sphinganine is a substrate of ASAH1ProteinRhea RHEA:45448Inferred only
- sphinganine is a substrate of CERS1ProteinRhea RHEA:36547Inferred only
- sphinganine is a substrate of CERS1ProteinRhea RHEA:36615Inferred only
- sphinganine is a substrate of CERS1ProteinRhea RHEA:36555Inferred only
- sphinganine is a substrate of CERS1ProteinRhea RHEA:34735Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:33591Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36715Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36667Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36627Inferred only
Show the remaining 35
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36619Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36535Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36575Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36539Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36555Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:33351Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36547Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36719Inferred only
- sphinganine is a substrate of CERS2ProteinRhea RHEA:36767Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:36627Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:33351Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:33591Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:36535Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:36547Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:36615Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:36619Inferred only
- sphinganine is a substrate of CERS3ProteinRhea RHEA:36675Inferred only
- sphinganine is a substrate of CERS4ProteinRhea RHEA:36535Inferred only
- sphinganine is a substrate of CERS4ProteinRhea RHEA:33591Inferred only
- sphinganine is a substrate of CERS4ProteinRhea RHEA:36547Inferred only
- sphinganine is a substrate of CERS4ProteinRhea RHEA:34735Inferred only
- sphinganine is a substrate of CERS4ProteinRhea RHEA:33351Inferred only
- sphinganine is a substrate of CERS4ProteinRhea RHEA:36555Inferred only
- sphinganine is a substrate of CERS5ProteinRhea RHEA:34735Inferred only
- sphinganine is a substrate of CERS5ProteinRhea RHEA:36571Inferred only
- sphinganine is a substrate of CERS5ProteinRhea RHEA:36575Inferred only
- sphinganine is a substrate of CERS5ProteinRhea RHEA:36539Inferred only
- sphinganine is a substrate of CERS5ProteinRhea RHEA:36547Inferred only
- sphinganine is a substrate of CERS5ProteinRhea RHEA:36647Inferred only
- sphinganine is a substrate of CERS6ProteinRhea RHEA:36547Inferred only
- sphinganine is a substrate of CERS6ProteinRhea RHEA:36571Inferred only
- sphinganine is a substrate of CERS6ProteinRhea RHEA:36539Inferred only
- sphinganine is a substrate of CERS6ProteinRhea RHEA:34735Inferred only
- sphinganine is a substrate of SPHK1ProteinRhea RHEA:15465Inferred only
- sphinganine is a substrate of SPHK2ProteinRhea RHEA:15465Inferred only
Reactions
37 reactions
sphinganine+ATP(4-)sphinganine 1-phosphate+ADP(3-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:15465CC BY 4.0Reference data
sphinganine+NADP(3-)3-oxosphinganine+NADPH(4-)+hydron
Catalysed by KDSR
Reaction pageRight to leftBalanced
Rhea RHEA:22640CC BY 4.0Reference data
sphinganine 1-phosphate+watersphinganine+hydrogenphosphate
Reaction pageLeft to rightBalanced
Rhea RHEA:27514CC BY 4.0Reference data
hexacosanoyl-CoA+sphinganineN-hexacosanoylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS3 or CERS2 or CERS4
Reaction pageLeft to rightBalanced
Rhea RHEA:33351CC BY 4.0Reference data
CHEBI:134414+sphinganineCHEBI:52372+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:33491CC BY 4.0Reference data
sphinganine+2Fe(II)-[cytochrome b5]+dioxygen+2hydron(4R)-hydroxysphinganine+2Fe(III)-[cytochrome b5]+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:33519CC BY 4.0Reference data
an N-acylsphinganine+watersphinganine+a fatty acid
Catalysed by ACER2 or ACER1 or ACER3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33551CC BY 4.0Reference data
tetracosanoyl-CoA+sphinganineN-tetracosanoylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS3 or CERS2 or CERS4
Reaction pageLeft to rightBalanced
Rhea RHEA:33591CC BY 4.0Reference data
N-tetracosanoylsphinganine+watertetracosanoate+sphinganine
Reaction pageDirection not assertedBalanced
Rhea RHEA:33843CC BY 4.0Reference data
a fatty acyl-CoA+sphinganinean N-acylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS1 or CERS6 or CERS5 or CERS4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:34735CC BY 4.0Reference data
docosanoyl-CoA+sphinganineN-docosanoylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS3 or CERS2 or CERS4
Reaction pageLeft to rightBalanced
Rhea RHEA:36535CC BY 4.0Reference data
sphinganine+hexadecanoyl-CoAN-hexadecanoylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS6 or CERS5 or CERS2
Reaction pageLeft to rightBalanced
Rhea RHEA:36539CC BY 4.0Reference data
Other names
4 names
Resolves to: sphinganine
- Also called
- C18-sphinganineC18-sphinganine(1+)d18:0(1+)
- Systematic name
- (2S,3R)-1,3-dihydroxyoctadecan-2-aminium