Compound
sphinganine 1-phosphate
The anion resulting from the addition of a proton to the amino group and the removal of the two acidic protons from the phosphate group of sphinganine 1-phosphate.
Definition from ChEBI (CHEBI:57939), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C18H39NO5P
- Mass
- 380.486 g/mol
- Charge
- -1
- InChIKey
- YHEDRJPUIRMZMP-ZWKOTPCHSA-M
- SMILES
- CCCCCCCCCCCCCCC[C@@H](O)[C@@H]([NH3+])COP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
8 entities
8 entities reached.
0 reported hops8 assembled from the scaffold
- SGPL1ProteinUNIPROT:O95470substrate ofInferred only24 paths12 endpoints
- SGPP1ProteinUNIPROT:Q9BX95substrate ofInferred only18 paths9 endpoints
- SGPP2ProteinUNIPROT:Q8IWX5substrate ofInferred only9 paths9 endpoints
- PLPP1ProteinUNIPROT:O14494substrate ofInferred only9 paths9 endpoints
- PLPP2ProteinUNIPROT:O43688substrate ofInferred only9 paths9 endpoints
- PLPP3ProteinUNIPROT:O14495substrate ofInferred only8 paths8 endpoints
- SPNS2ProteinUNIPROT:Q8IVW8transported byInferred only4 paths4 endpoints
- MFSD2BProteinUNIPROT:A6NFX1transported byInferred only4 paths4 endpoints
What the reference databases state
Statements
16 statements
16 statements · 2 reference databases · Subject: sphinganine 1-phosphate · Sources: Human-GEM, Rhea
- sphinganine 1-phosphate is converted to CHEBI:16566CompoundHuman-GEM MAR08233Inferred only
- sphinganine 1-phosphate is converted to CHEBI:16566CompoundHuman-GEM MAR00746Inferred only
- CHEBI:16566 is converted to sphinganine 1-phosphateCompoundHuman-GEM MAR00744Inferred only
- CHEBI:16566 is converted to sphinganine 1-phosphateCompoundHuman-GEM MAR12083Inferred only
- sphinganine 1-phosphate is converted to sphinganineCompoundRhea RHEA:27514Inferred only
- sphinganine is converted to sphinganine 1-phosphateCompoundRhea RHEA:15465Inferred only
- sphinganine 1-phosphate is a substrate of PLPP1ProteinHuman-GEM MAR00746Inferred only
- sphinganine 1-phosphate is a substrate of PLPP2ProteinHuman-GEM MAR00746Inferred only
- sphinganine 1-phosphate is a substrate of PLPP3ProteinHuman-GEM MAR00746Inferred only
- sphinganine 1-phosphate is a substrate of SGPL1ProteinRhea RHEA:18593Inferred only
- sphinganine 1-phosphate is a substrate of SGPL1ProteinHuman-GEM MAR08237Inferred only
- sphinganine 1-phosphate is a substrate of SGPP1ProteinHuman-GEM MAR08233Inferred only
Show the remaining 4
- sphinganine 1-phosphate is a substrate of SGPP1ProteinRhea RHEA:27514Inferred only
- sphinganine 1-phosphate is a substrate of SGPP2ProteinRhea RHEA:27514Inferred only
- sphinganine 1-phosphate is transported by MFSD2BProteinRhea RHEA:38671Inferred only
- sphinganine 1-phosphate is transported by SPNS2ProteinRhea RHEA:38671Inferred only
Reactions
13 reactions
ATP+CHEBI:16566ADP+proton+sphinganine 1-phosphate
Catalysed by SPHK2 or DBP or SPHK1
Reaction pageLeft to rightBalancedEC 2.7.1.91cytosol
Human-GEM MAR00744CC BY 4.0Reference data
water+sphinganine 1-phosphatephosphate(3-)+CHEBI:16566
Catalysed by PLPP1 or PLPP2 or PLPP3
Reaction pageLeft to rightBalancedEC 3.1.3.4cytosol
Human-GEM MAR00746CC BY 4.0Reference data
O-phosphoethanolamine+hexadecanalsphinganine 1-phosphate
Catalysed by SGPL1
Reaction pageLeft to rightBalancedEC 4.1.2.27cytosol
Human-GEM MAR00748CC BY 4.0Reference data
water+sphinganine 1-phosphatephosphate(3-)+CHEBI:16566
Catalysed by SGPP1
Reaction pageLeft to rightBalancedEC 3.1.3.-endoplasmic reticulum
Human-GEM MAR08233CC BY 4.0Reference data
sphinganine 1-phosphateO-phosphoethanolamine+hexadecanal
Catalysed by SGPL1
Reaction pageLeft to rightBalancedEC 4.1.2.27endoplasmic reticulum
Human-GEM MAR08237CC BY 4.0Reference data
sphinganine 1-phosphatesphinganine 1-phosphate
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR08239CC BY 4.0Reference data
sphinganine 1-phosphatesphinganine 1-phosphate
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR08240CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09410CC BY 4.0Reference data
ATP+CHEBI:16566ADP+proton+sphinganine 1-phosphate
Catalysed by SPHK2
Reaction pageLeft to rightBalancedEC 2.7.1.91nucleus
Human-GEM MAR12083CC BY 4.0Reference data
sphinganine+ATP(4-)sphinganine 1-phosphate+ADP(3-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:15465CC BY 4.0Reference data
sphinganine 1-phosphatehexadecanal+phosphoethanolamine
Catalysed by SGPL1
Reaction pageLeft to rightBalanced
Rhea RHEA:18593CC BY 4.0Reference data
sphinganine 1-phosphate+watersphinganine+hydrogenphosphate
Reaction pageLeft to rightBalanced
Rhea RHEA:27514CC BY 4.0Reference data
Where it reaches
4 systems, 6 regions, 8 tissues, 8 transporter routes — routes, not measurements: transporters known to carry sphinganine 1-phosphate are expressed there, and no source reports it arriving.
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Other names
3 names
Resolves to: sphinganine 1-phosphate
- Also called
- (2S,3R)-2-ammonio-3-hydroxyoctadecyl phosphate(2S,3R)-3-hydroxy-1-(phosphonatooxy)octadecan-2-aminium
- Systematic name
- (2S,3R)-2-azaniumyl-3-hydroxyoctadecyl phosphate