CHEBI:15746

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

565 compounds within 3 steps: 5 in 1, 120 in 2, 440 in 3

Two steps

(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by SAT1, SAT2, CPT1A, CPT1C and 1 morecytosolOne of 3 routes
dodecanedioyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Activation of dodecanedioic acid
Catalysed by SAT1, SAT2cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Production of Sebacoylcarnitine
Catalysed by SAT1, SAT2, CPT1A, CPT1C and 1 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Production of Suberylcarnitine
Catalysed by SAT1, SAT2, CPT1A, CPT1C and 1 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by SAT1, SAT2cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by SAT1, SAT2, CPT1A, CPT1C and 1 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by SAT1, SAT2, CRAT, CROTcytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by SAT1, SAT2, ACAA1, HSD17B4 and 2 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Production of Hexadecanedioylcarnitine
Catalysed by SAT1, SAT2, CPT1A, CPT1C and 1 morecytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. fatty-acid-CoA ligase
Catalysed by SAT1, SAT2, SLC27A2cytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by SAT1, SAT2, ACSM4, ACSM1 and 4 morecytosolOne of 3 routes
(5Z)-tetradecenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by SAT1, SAT2, ACADM, ECHS1 and 2 morecytosol, mitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by SAT1, SAT2, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. diamine N-acetyltransferase (N1-acetylspermine)
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by SAT1, SAT2, SLC27A2, ACSL4 and 6 morecytosolOne of 4 routes

Three steps

N(omega)-methyl-L-arginineReach from here →
Catalysed by SAT1, SAT2, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrixOne of 2 routes
AReach from here →