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Proteins/UNIPROT:O43826
Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Responsible for glucose production through glycogenolysis and gluconeogenesis and plays a central role in homeostatic regulation of blood glucose levels..
Function from UniProtKB (O43826), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
3 rows
170 statements
170 statements · 4 reference databases · Subject: SLC37A4 · Sources: Hetionet, Human-GEM, Reactome, Rhea
4 reactions
Transported by SLC37A4
Reaction pageReversibleBalancedendoplasmic reticulum, cytosol
Human-GEM MAR01621CC BY 4.0Reference data
D-glucopyranose 6-phosphateD-glucopyranose 6-phosphate
Transported by SLC37A4
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR04856CC BY 4.0Reference data
7 names
Resolves to: SLC37A4
Transported by SLC37A4
Reaction pageLeft to rightBalancedcytosol, endoplasmic reticulum
Human-GEM MAR06386CC BY 4.0Reference data
D-glucose 6-phosphate+hydrogenphosphateD-glucose 6-phosphate+hydrogenphosphate
Transported by SLC37A4 or SLC37A1 or SLC37A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:71535CC BY 4.0Reference data