an N(2)-acyl-L-glutamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

611 compounds within 3 steps: 2 in 1, 108 in 2, 501 in 3

Three steps

1-octadecanoyl-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. 1-acylglycerol-3-phosphate pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 2 moremitochondrial matrix, cytosolOne of 3 routes
1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GLYATL1B, GLYATL1, AGPAT2, GPAT3 and 3 morecytosol
3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA
Catalysed by GLYATL1B, GLYATL1, ELOVL4cytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3cytosol
(2E)-eicosenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. acyl-CoA oxidase (eicosanoyl-CoA)
Catalysed by GLYATL1B, GLYATL1, ACOX3, ACOX1cytosol, peroxisomeOne of 4 routes
(2E)-docosenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. acyl-CoA oxidase (docosanoyl-CoA)
Catalysed by GLYATL1B, GLYATL1, ACOX3, ACOX1cytosol, peroxisomeOne of 4 routes
(2E)-tetracosenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. acyl-CoA oxidase (tetracosanoyl-CoA)
Catalysed by GLYATL1B, GLYATL1, ACOX3, ACOX1cytosol, peroxisomeOne of 3 routes
1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GLYATL1B, GLYATL1, AGPAT1cytosol
1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3, MBOAT1cytosol
1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-hexadecenoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by GLYATL1B, GLYATL1, MBOAT1cytosol
1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serine + CoA
Catalysed by GLYATL1B, GLYATL1, MBOAT1, LPGAT1cytosol
a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. sn-glycerol 3-phosphate + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphate + CoA
3. a 1-acyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 3 more
1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GLYATL1B, GLYATL1, ABHD5cytosol
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. 1-acylglycerol-3-phosphate pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 2 moremitochondrial matrix, cytosolOne of 2 routes
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT1cytosol
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPGAT1cytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3cytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. dodecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3, LPCAT1cytosol
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3cytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPGAT1cytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL1B, GLYATL1, LPGAT1cytosol
1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. a 1-acyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3cytosol
1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT3cytosol
1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GLYATL1B, GLYATL1, AGPAT1cytosol
1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT2, AGPAT3 and 1 morecytosol
(11Z)-octadecenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 5 moremitochondrial matrix, cytosolOne of 4 routes
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by GLYATL1B, GLYATL1, LCLAT1cytosol
1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, LCLAT1cytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, LCLAT1cytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, LCLAT1cytosol
1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA = 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, LCLAT1cytosol
1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, LCLAT1cytosol
1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT4cytosol
1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. tetradecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT1cytosol
1-dodecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA = 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, MOGAT2, MOGAT1cytosol
1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, MOGAT2, MOGAT1cytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, MOGAT2, MOGAT1cytosol
1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, MOGAT2, MOGAT1cytosol
eicosan-1-olReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
Catalysed by GLYATL1B, GLYATL1, FAR1, FAR2cytosol
hexadecyl (9Z)-hexadecenoateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. hexadecan-1-ol + (9Z)-hexadecenoyl-CoA = hexadecyl (9Z)-hexadecenoate + CoA
Catalysed by GLYATL1B, GLYATL1, AWAT1, AWAT2cytosol
hexadecyl octadecanoateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by GLYATL1B, GLYATL1, AWAT1, AWAT2cytosol
dodecanedioyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. Activation of dodecanedioic acid
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 2 moremitochondrial matrix, cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. Production of Sebacoylcarnitine
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 5 moremitochondrial matrix, cytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. Production of Suberylcarnitine
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 5 moremitochondrial matrix, cytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 2 moremitochondrial matrix, cytosolOne of 4 routes
(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by GLYATL1B, GLYATL1, ELOVL1cytosol, endoplasmic reticulumOne of 2 routes
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)
Catalysed by GLYATL1B, GLYATL1, LCLAT1, LPCAT1 and 3 moreOne of 2 routes
3-oxo-(11Z)-octadecenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
3. (9Z)-hexadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA
Catalysed by GLYATL1B, GLYATL1, ELOVL6, ELOVL5cytosol
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by GLYATL1B, GLYATL1, GPAT3, GPAT2 and 5 moremitochondrial matrix, cytosolOne of 2 routes
2-aminoprop-2-enoateReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. D-serine(in) + L-glutamine(out) + Na(+)(out) = D-serine(out) + L-glutamine(in) + Na(+)(in)
3. D-serine = 2-aminoprop-2-enoate + H2O
Catalysed by GLYATL1B, GLYATL1, SLC1A5, SRRinner side of the membrane, outer side of the membrane