Compound

3-oxo-(11Z)-octadecenoyl-CoA

A 3-oxo-fatty acyl-CoA(4−) obtained by deprotonation of the phosphate and diphosphate OH groups of (11Z)-3-oxooctadecenoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:76555), read 2026-09-23. CC BY 4.0.

CHEBI:76555ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound, anion
Formula: C39H62N7O18P3S
Mass: 1041.945 g/mol
Charge: -4
InChIKey: OUROWZUTGFHRJE-SAIINBSPSA-J
SMILES: CCCCCC/C=CCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Statements

10 statements

10 statements · 2 reference databases · Subject: 3-oxo-(11Z)-octadecenoyl-CoA · Sources: Human-GEM, Rhea

Order

3-oxo-(11Z)-octadecenoyl-CoA is converted to (9Z)-hexadecenoyl-CoACompoundRhea RHEA:83251Inferred only
(9Z)-hexadecenoyl-CoA is converted to 3-oxo-(11Z)-octadecenoyl-CoACompoundRhea RHEA:39675Inferred only
(R)-3-hydroxy-(11Z)-octadecenoyl-CoA is converted to 3-oxo-(11Z)-octadecenoyl-CoACompoundRhea RHEA:39683Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is converted to (R)-3-hydroxy-(11Z)-octadecenoyl-CoACompoundRhea RHEA:39683Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03363Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is a substrate of ACAA2ProteinHuman-GEM MAR03247Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03247Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is a substrate of HADHBProteinRhea RHEA:83251Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is a substrate of HADHBProteinHuman-GEM MAR03247Inferred only
3-oxo-(11Z)-octadecenoyl-CoA is a substrate of MYO5BProteinHuman-GEM MAR03363Inferred only

Reactions

8 reactions

MAM00170m+NAD(+)3-oxo-(11Z)-octadecenoyl-CoA+proton+NADH(2-)
Catalysed by HADHA & HADH & HSD17B10
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211mitochondrial matrix
Human-GEM MAR03246CC BY 4.0Reference data
3-oxo-(11Z)-octadecenoyl-CoA+CHEBI:1146900CHEBI:15351+(9Z)-hexadecenoyl-CoA
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211mitochondrial matrix
Human-GEM MAR03247CC BY 4.0Reference data
MAM00170x+NAD(+)3-oxo-(11Z)-octadecenoyl-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211peroxisome
Human-GEM MAR03362CC BY 4.0Reference data
3-oxo-(11Z)-octadecenoyl-CoA+CHEBI:1146900CHEBI:15351+(9Z)-hexadecenoyl-CoA
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03363CC BY 4.0Reference data
(9Z)-hexadecenoyl-CoA+malonyl-CoA+hydron3-oxo-(11Z)-octadecenoyl-CoA+carbon dioxide+coenzyme A(4-)
Catalysed by ELOVL6 or ELOVL5
Reaction pageLeft to rightBalanced
Rhea RHEA:39675CC BY 4.0Reference data
3-oxo-(11Z)-octadecenoyl-CoA+NADPH(4-)+hydron(R)-3-hydroxy-(11Z)-octadecenoyl-CoA+NADP(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:39683CC BY 4.0Reference data
CHEBI:232532+NAD(1-)3-oxo-(11Z)-octadecenoyl-CoA+NADH(2-)+hydron
Catalysed by HADHA
Reaction pageLeft to rightBalanced
Rhea RHEA:83031CC BY 4.0Reference data
3-oxo-(11Z)-octadecenoyl-CoA+coenzyme A(4-)(9Z)-hexadecenoyl-CoA+acetyl-CoA
Catalysed by HADHB
Reaction pageLeft to rightBalanced
Rhea RHEA:83251CC BY 4.0Reference data

Other names

13 names

Resolves to: 3-oxo-(11Z)-octadecenoyl-CoA

Also called: (11Z)-3-ketooctadecenoyl-CoA(4-)(11Z)-3-ketooctadecenoyl-CoA(4−)(11Z)-3-ketooctadecenoyl-coenzyme A(4-)(11Z)-3-ketooctadecenoyl-coenzyme A(4−)(11Z)-3-oxooctadecenoyl-coenzyme A(4-)(11Z)-3-oxooctadecenoyl-coenzyme A(4−)3-keto-(11Z)-octadecenoyl-coenzyme A(4-)3-keto-(11Z)-octadecenoyl-coenzyme A(4−)3-oxo-(11Z)-octadecenoyl-CoA(4-)3-oxo-(11Z)-octadecenoyl-CoA(4−)3-oxo-(11Z)-octadecenoyl-coenzyme A(4-)3-oxo-(11Z)-octadecenoyl-coenzyme A(4−)
Systematic name: 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-4-({3-[(2-{[(11Z)-3-oxooctadec-11-enoyl]sulfanyl}ethyl)amino]-3-oxopropyl}amino)-2,2-dimethyl-4-oxobutyl] diphosphate}