(11Z)-octadecenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

636 compounds within 3 steps: 7 in 1, 156 in 2, 473 in 3

Three steps

a triacyl-sn-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
Catalysed by FADS2, DGAT1, MOGAT2, AWAT2 and 3 morecytosol
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by FADS2, LCLAT1, LPCAT1, GPAMcytosol
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 3 moremitochondrial matrix
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositolReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosol
3-oxoeicosasphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. octadecanoyl-CoA + L-serine + H(+) = 3-oxoeicosasphinganine + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
N-hexadecanoyl-(4R)-hydroxysphinganineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (4R)-hydroxysphinganine + hexadecanoyl-CoA = N-hexadecanoyl-(4R)-hydroxysphinganine + CoA + H(+)
Catalysed by HADHA, ACADVL, HADHB, SCD and 3 moremitochondrial matrix
3-oxoeicosanoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. very-long-chain 3-oxoacyl-CoA synthase (malonyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 13 morecytosolOne of 2 routes
N-docosanoylsphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. docosanoyl-CoA + sphinganine = N-docosanoylsphinganine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 10 morecytosol
N-eicosanoylsphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + sphinganine = N-eicosanoylsphinganine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 10 morecytosol
N-(octadecanoyl)-sphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 12 morecytosol
N-hexadecanoylsphinganineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. sphinganine + hexadecanoyl-CoA = N-hexadecanoylsphinganine + CoA + H(+)
Catalysed by HADHA, ACADVL, HADHB, SCD and 4 moremitochondrial matrix
N-(tetradecanoyl)-sphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. sphinganine + tetradecanoyl-CoA = N-(tetradecanoyl)-sphinganine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
3-oxohexadecasphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + L-serine + H(+) = 3-oxohexadecasphinganine + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
3-oxotetradecasphinganineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. dodecanoyl-CoA + L-serine + H(+) = 3-oxotetradecasphinganine + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
Mo-molybdopterinReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by CPT1A, CPT1C, CPT1B, MOCOScytosol, mitochondrial matrix
3-oxooctadecanoyl-CoAReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. hexadecanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctadecanoyl-CoA + CO2 + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 4 moremitochondrial matrixOne of 3 routes
3-oxodocosanoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. very-long-chain 3-oxoacyl-CoA synthase (eicosanoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 14 morecytosolOne of 3 routes
3-oxo-(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. fatty acyl-CoA desaturase (N-C18:2CoA -> N-C18:3CoA)
3. (6Z,9Z,12Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z)-eicosatrienoyl-CoA + CO2 + CoA
Catalysed by FADS2, FADS1, ELOVL7, ELOVL5cytosol
3-oxo-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearidonic acid)
3. (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
(8Z,11Z,14Z)-eicosatrienoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. Carnitine O-Palmitoyltransferase
3. Utilized Transport
Catalysed by CPT1A, CPT1C, CPT1Bcytosol, endoplasmic reticulumOne of 2 routes
1-dodecanoyl-sn-glycerol 3-phosphateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosolOne of 2 routes
1-tetradecanoyl-sn-glycerol 3-phosphateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosol
1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 4 moremitochondrial matrix
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosol
1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosol
1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1,2-dihexadecanoyl-sn-glycero-3-phosphateReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
N-dodecanoylsphing-4-enineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. acyl-CoA:sphingosine N-acyltransferase
3. N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine
Catalysed by CPT1A, CPT1C, CPT1B, ASAH1 and 4 morecytosol, Golgi apparatus
N-tetradecanoylsphing-4-enineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. acyl-CoA:sphingosine N-acyltransferase
3. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
Catalysed by CPT1A, CPT1C, CPT1B, ASAH1 and 3 morecytosol, Golgi apparatus
N-hexadecanoylsphing-4-enineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. sphing-4-enine + hexadecanoyl-CoA = N-hexadecanoylsphing-4-enine + CoA + H(+)
Catalysed by HADHA, ACADVL, HADHB, SCD and 5 moremitochondrial matrixOne of 3 routes
N-octadecanoylsphing-4-enineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. sphing-4-enine + octadecanoyl-CoA = N-octadecanoylsphing-4-enine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 10 morecytosolOne of 3 routes
N-eicosanoyl-sphing-4-enineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + sphing-4-enine = N-eicosanoyl-sphing-4-enine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosolOne of 2 routes
N-tetracosanoyl-sphing-4-enineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. tetracosanoyl-CoA + sphing-4-enine = N-tetracosanoyl-sphing-4-enine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosolOne of 5 routes
1,2-dihexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosolOne of 2 routes
1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. octadecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosol
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
3-oxo-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (EPA)
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
(9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DPA)
3. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + malonyl-CoA + H(+) = (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
3-oxooctacosanyol-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (cerotic acid)
3. hexacosanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctacosanyol-CoA + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
3-oxotetracosanoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. very-long-chain 3-oxoacyl-CoA synthase (docosanoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 14 morecytosolOne of 3 routes
3-oxohexacosanoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. very-long-chain 3-oxoacyl-CoA synthase (malonyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 14 morecytosolOne of 3 routes