Compound
N-dodecanoylsphing-4-enine
A N-acylsphingosine in which the ceramide N-acyl group is specified as dodecanoyl (lauroyl).
Definition from ChEBI (CHEBI:72956), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C30H59NO3
- Mass
- 481.806 g/mol
- Charge
- 0
- InChIKey
- HXFPPRPLRSPNIB-VARSQMIESA-N
- SMILES
- CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- GBA1ProteinUNIPROT:P04062substrate ofInferred only32 paths16 endpoints
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only26 paths26 endpoints
- GBA2ProteinUNIPROT:Q9HCG7substrate ofInferred only8 paths8 endpoints
- ASAH2ProteinUNIPROT:Q9NR71substrate ofInferred only7 paths7 endpoints
- NAAAProteinUNIPROT:Q02083substrate ofInferred only6 paths3 endpoints
- ACER2ProteinUNIPROT:Q5QJU3substrate ofInferred only4 paths4 endpoints
What the reference databases state
Chemical structure
- N-dodecanoylsphing-4-enine has the functional parent dodecanoic acidCompoundChEBI CHEBI:72956Inferred only
Statements
8 statements
8 statements · 2 reference databases · Subject: N-dodecanoylsphing-4-enine · Sources: Human-GEM, Rhea
- N-dodecanoylsphing-4-enine is a substrate of ACER2ProteinRhea RHEA:41291Inferred only
- N-dodecanoylsphing-4-enine is a substrate of ASAH1ProteinRhea RHEA:41291Inferred only
- N-dodecanoylsphing-4-enine is a substrate of ASAH2ProteinRhea RHEA:41291Inferred only
- N-dodecanoylsphing-4-enine is a substrate of GBA1ProteinRhea RHEA:70307Inferred only
- N-dodecanoylsphing-4-enine is a substrate of GBA1ProteinRhea RHEA:70255Inferred only
- N-dodecanoylsphing-4-enine is a substrate of GBA2ProteinRhea RHEA:70255Inferred only
- N-dodecanoylsphing-4-enine is a substrate of NAAAProteinHuman-GEM MAR20097Inferred only
- N-dodecanoylsphing-4-enine is a substrate of NAAAProteinRhea RHEA:41291Inferred only
Reactions
4 reactions
water+N-dodecanoylsphing-4-eninedodecanoate+sphing-4-enine
Catalysed by NAAA
Reaction pageLeft to rightBalancedEC 3.5.1.23cytosol
Human-GEM MAR20097CC BY 4.0Reference data
N-dodecanoylsphing-4-enine+waterdodecanoate+sphing-4-enine
Catalysed by NAAA or ASAH1 or ACER2 or ASAH2
Reaction pageReversibleBalanced
Rhea RHEA:41291CC BY 4.0Reference data
1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enine+cholesterolcholesteryl 3-beta-D-galactoside+N-dodecanoylsphing-4-enine
Reaction pageReversibleBalanced
Rhea RHEA:70255CC BY 4.0Reference data
beta-D-glucosyl-N-dodecanoylsphing-4-enine+cholesterolN-dodecanoylsphing-4-enine+cholesteryl 3-beta-D-glucoside
Catalysed by GBA1
Reaction pageReversibleBalanced
Rhea RHEA:70307CC BY 4.0Reference data
Other names
15 names
Resolves to: N-dodecanoylsphing-4-enine
- Also called
- Cer 30:1;O2Cer(d18:1(4E)/12:0)Cer(d18:1/12:0)Cer[NS]Dodecyl sphingosineLaurylsphingosineN-(dodecanoyl)-ceramideN-(dodecanoyl)-sphing-4-enineN-(dodecanoyl)ceramideN-(dodecanoyl)sphing-4-enineN-(lauroyl)ceramideN-(lauroyl)sphing-4-enineN-lauroylsphing-4-enineN-lauroylsphingosine
- Systematic name
- N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]dodecanamide