N-tetradecanoylsphing-4-enine

Three steps

• a 1,2-diacyl-sn-glycerolReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. ceramide:phosphatidylcholine cholinephosphotransferase

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 7 moreGolgi apparatusOne of 6 routes

• dodecanoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 14 routes

• D-glucosyl-N-acylsphingosineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. UDP-glucose:N-acylsphingosine D-glucosyltransferase

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 6 morecytosolOne of 2 routes

• a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 6 moreOne of 2 routes

• a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-xyloside + an N-acylsphing-4-enine

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 7 moreOne of 2 routes

• beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
  3. N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, ACER1 and 2 more

• a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 6 moreOne of 2 routes

• (7Z)-tetradecenoyl-CoAReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. stearoyl-CoA 9-desaturase (myristoyl-CoA)

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 9 morecytosol

• docosanoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• octadecanoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 13 routes

• alpha-linolenic acidReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• elaidic acidReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 13 routes

• alpha-D-galactoseReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
  3. galactosylceramidase (psychosine)

  Catalysed by ASAH1, ACER2, ASAH2, GALCcytosol, lysosome

• all-cis-docosa-4,7,10,13,16,19-hexaenoic acidReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 moreOne of 3 routes

• a fatty acidReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 8 more

• phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• acetateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2

• (9Z)-octadecenoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 14 routes

• hexacosanoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• tetracosanoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 13 routes

• an N-acylsphinganineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. N-acylsphingosine amidohydrolase

  Catalysed by ASAH1, ACER2, ASAH2, ACER1 and 1 morecytosol

• eicosanoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 13 routes

• (9Z)-hexadecenoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• (15Z)-tetracosenoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 13 routes

• (5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• (11Z)-eicosenoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• 1-O-hexadecyl-sn-glycerolReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 2 more

• 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 moreOne of 2 routes

• 3-oxohexadecanoyl-CoAReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. tetradecanoyl-CoA + malonyl-CoA + H(+) = 3-oxohexadecanoyl-CoA + CO2 + CoA

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 9 morecytosol

• dodecanoyl-CoAReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. Fatty Acid Beta Oxidation (C14->C12), Mitochondrial

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 10 morecytosol, mitochondrial matrixOne of 2 routes

• an N-acylsphing-4-enine 1-phosphateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
  3. an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, CERS1 and 7 more

• a 2-acyl-sn-glycero-3-phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphocholine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• a 1-acyl-sn-glycero-3-phosphocholineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• phosphoethanolamineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. sphing-4-enine + ATP = sphing-4-enine 1-phosphate + ADP + H(+)
  3. sphing-4-enine 1-phosphate = (2E)-hexadecenal + phosphoethanolamine

  Catalysed by ASAH1, ACER2, ASAH2, SPHK2 and 2 more

• an acyl-CoAReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. acyl-CoA pool formation and breakdown

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 7 morecytosolOne of 3 routes

• (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• (2E)-tetradecenoyl-CoAReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. trans-tetradec-2-enoyl-CoA reductase

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 8 morecytosol, mitochondrial matrixOne of 5 routes

• a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• a 1-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• a 2-acyl-sn-glycero-3-phospho-L-serineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
  3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine

  Catalysed by ASAH1, ACER2, ASAH2, PAFAH2 and 1 more

• N-(tetradecanoyl)-sphinganineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. sphinganine + tetradecanoyl-CoA = N-(tetradecanoyl)-sphinganine + CoA + H(+)

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 9 morecytosol

• CHEBI:67119Reach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
  3. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase

  Catalysed by ASAH1, ACER2, ASAH2cytosol

• 3-oxohexadecasphinganineReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. tetradecanoyl-CoA + L-serine + H(+) = 3-oxohexadecasphinganine + CO2 + CoA

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 9 morecytosol

• (8Z,11Z,14Z)-eicosatrienoateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ASAH1, ACER2, ASAH2cytosol, extracellular spaceOne of 12 routes

• 1-tetradecanoyl-sn-glycerol 3-phosphateReach from here →
  1. N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)

  Catalysed by ASAH1, ACER2, ASAH2, SLC27A2 and 11 morecytosol