(4R)-hydroxysphinganine 1-phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

27 compounds within 3 steps: 2 in 1, 6 in 2, 19 in 3

One step

O-phosphoethanolamineReach from here →
1. Sphingosine-1-Phosphate Lyase 1 (Phytosphingosine-1-Phosphate, Cytosol)
No catalyst recordedcytosol
(4R)-hydroxysphinganineReach from here →
1. (4R)-hydroxysphinganine 1-phosphate + H2O = (4R)-hydroxysphinganine + phosphate
Catalysed by SGPP2One of 2 routes

Two steps

Three steps

Sphingosine-1-Phosphate Lyase 1 (Phytosphingosine-1-Phosphate, Cytosol)

CTP:ethanolamine-phosphate cytidylyltransferase

Catalysed by PCYT2cytosol

sphinganine 1-phosphateReach from here →

Catalysed by SGPL1cytosol

N-hexadecanoyl-(4R)-hydroxysphinganineReach from here →

Catalysed by SGPP2, CERS6, CERS5

N-dodecanoyl-(4R)-hydroxysphinganineReach from here →

Catalysed by SGPP2, ASAH1

Catalysed by PCYT2, SELENOI, CEPT1

cytosol

CHEBI:16132Reach from here →

Catalysed by ETNPPL, DERAcytosol

CHEBI:16566Reach from here →

Catalysed by SGPL1, PLPP1, PLPP3, PLPP2cytosolOne of 2 routes

1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PCYT2, SELENOI, CEPT1cytosol

hexadecanalReach from here →

Catalysed by SGPL1cytosol, endoplasmic reticulumOne of 2 routes

a 1,2-diacyl-sn-glycerolReach from here →

Catalysed by SGPP2, CERS6, CERS5, SGMS1 and 1 moreOne of 2 routes

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →

Catalysed by PHOSPHO1, FAAHcytosol

acetateReach from here →

Catalysed by ETNPPL, ALDH3A1, ALDH3B1, ALDH1A3 and 1 morecytosolOne of 4 routes

sphinganineReach from here →

Catalysed by SGPL1, SGPP2, SGPP1cytosol

phosphoethanolamineReach from here →

Catalysed by PHOSPHO1, CHKA, ETNK1, ETNK2 and 1 morecytosolOne of 4 routes

a 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PCYT2, SELENOIcytosol

2-deoxy-D-ribose 5-phosphateReach from here →

Catalysed by ETNPPL, DERAcytosol

a 1,2-diacyl-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PCYT2, SELENOI, CEPT1cytosol

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PCYT2, CEPT1cytosol

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PCYT2, CEPT1cytosol

a 1-O-alkyl-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by PHOSPHO1, ENPP2cytosol

N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholineReach from here →

Catalysed by SGPP2, CERS6, CERS5, SGMS1 and 1 more

N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamineReach from here →

Catalysed by SGPP2, CERS6, CERS5, SGMS2 and 1 more