Compound
(4R)-hydroxysphinganine 1-phosphate
An anionic phospholipid obtained by deprotonation of the phosphate OH groups and protonation of the amino group of phytosphingosine 1-phosphate; major species at pH 7.3.
Definition from ChEBI (CHEBI:64795), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C18H39NO6P
- Mass
- 396.485 g/mol
- Charge
- -1
- InChIKey
- AYGOSKULTISFCW-KSZLIROESA-M
- SMILES
- CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H]([NH3+])COP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 2 reference databases · Subject: (4R)-hydroxysphinganine 1-phosphate · Sources: Human-GEM, Rhea
- (4R)-hydroxysphinganine 1-phosphate is converted to (4R)-hydroxysphinganineCompoundRhea RHEA:33067Inferred only
- (4R)-hydroxysphinganine 1-phosphate is converted to (4R)-hydroxysphinganineCompoundRhea RHEA:33563Inferred only
- (4R)-hydroxysphinganine is converted to (4R)-hydroxysphinganine 1-phosphateCompoundHuman-GEM MAR12081Inferred only
- (4R)-hydroxysphinganine is converted to (4R)-hydroxysphinganine 1-phosphateCompoundRhea RHEA:33563Inferred only
- (4R)-hydroxysphinganine 1-phosphate is a substrate of SGPP2ProteinRhea RHEA:33067Inferred only
- (4R)-hydroxysphinganine 1-phosphate is a substrate of SPHK2ProteinRhea RHEA:33563Inferred only
Reactions
5 reactions
ATP+(4R)-hydroxysphinganineADP+proton+(4R)-hydroxysphinganine 1-phosphate
Catalysed by SPHK1
Reaction pageLeft to rightBalancedEC 2.7.1.91cytosol
Human-GEM MAR12081CC BY 4.0Reference data
(4R)-hydroxysphinganine 1-phosphateO-phosphoethanolamine+MAM03661c
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR12111CC BY 4.0Reference data
(4R)-hydroxysphinganine 1-phosphate+water(4R)-hydroxysphinganine+hydrogenphosphate
Catalysed by SGPP2
Reaction pageLeft to rightBalanced
Rhea RHEA:33067CC BY 4.0Reference data
(4R)-hydroxysphinganine+ATP(4-)(4R)-hydroxysphinganine 1-phosphate+ADP(3-)+hydron
Catalysed by SPHK2
Reaction pageDirection not assertedBalanced
Rhea RHEA:33563CC BY 4.0Reference data
(4R)-hydroxysphinganine 1-phosphateCHEBI:138635+phosphoethanolamine
Reaction pageDirection not assertedBalanced
Rhea RHEA:55208CC BY 4.0Reference data
Other names
3 names
Resolves to: (4R)-hydroxysphinganine 1-phosphate
- Also called
- (2S,3S,4R)-2-ammonio-3,4-dihydroxyoctadecyl phosphatephytosphingosine 1-phosphate
- Systematic name
- (2S,3S,4R)-2-azaniumyl-3,4-dihydroxyoctadecyl phosphate