5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Catalysed by ATIC

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. IMP + H2O = inosine + phosphate

Catalysed by ATIC, NT5E, NT5C2, NT5C and 1 moreOne of 7 routes

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. IMP + NAD(+) + H2O = XMP + NADH + H(+)

Catalysed by ATIC, IMPDH2, IMPDH1

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)

Catalysed by ATIC, ADSS2, ADSS1

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. dGMP + inosine = 2'-deoxyguanosine + IMP

Catalysed by ATIC, NT5C2

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. dIMP + inosine = 2'-deoxyinosine + IMP

Catalysed by ATIC, NT5C2

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. dGMP + inosine = 2'-deoxyguanosine + IMP
3. dADP to dATP conversion

Catalysed by ATIC, NT5C2mitochondrial matrix

1. IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
2. IMP + H2O = inosine + phosphate
3. transport of adenosine and inosine (cytosol to extracellular)

Catalysed by ATIC, NT5E, NT5C2 and 1 more