a (3R)-3-hydroxyacyl-CoA

1. a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)

Catalysed by HSD17B4, HSD17B8

1. a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)
2. a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)

Catalysed by HSD17B4, HSD17B8, EHHADH, HADH and 1 more

1. a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA

Catalysed by HSD17B4, HSD17B8, ACAA1, SCP2 and 2 more

1. a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase

Catalysed by HSD17B4, HSD17B8, ACAA1, SCP2 and 6 moremitochondrial matrixOne of 16 routes

1. a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)