Compound
a (3R)-3-hydroxyacyl-CoA
The tetraanion of an (R)-3-hydroxyacyl-CoA compound.
Definition from ChEBI (CHEBI:57319), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C24H35N7O18P3SR
- Mass
- 834.557 g/mol
- Charge
- -4
- SMILES
- [1*][C@@H](O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
8 statements
8 statements · 1 reference database · Subject: a (3R)-3-hydroxyacyl-CoA · Sources: Rhea
- a (2E)-enoyl-CoA is converted to a (3R)-3-hydroxyacyl-CoACompoundRhea RHEA:26526Inferred only
- a (3S)-3-hydroxyacyl-CoA is converted to a (3R)-3-hydroxyacyl-CoACompoundRhea RHEA:34083Inferred only
- a (3R)-3-hydroxyacyl-CoA is converted to a (3S)-3-hydroxyacyl-CoACompoundRhea RHEA:34083Inferred only
- a (3R)-3-hydroxyacyl-CoA is converted to a 3-oxoacyl-CoACompoundRhea RHEA:32711Inferred only
- a 3-oxoacyl-CoA is converted to a (3R)-3-hydroxyacyl-CoACompoundRhea RHEA:22256Inferred only
- a (3R)-3-hydroxyacyl-CoA is converted to a 3-oxoacyl-CoACompoundRhea RHEA:22256Inferred only
- a (3R)-3-hydroxyacyl-CoA is a substrate of HSD17B4ProteinRhea RHEA:32711Inferred only
- a (3R)-3-hydroxyacyl-CoA is a substrate of HSD17B8ProteinRhea RHEA:32711Inferred only
Reactions
5 reactions
a (3R)-3-hydroxyacyl-CoA+NADP(3-)a 3-oxoacyl-CoA+NADPH(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:22256CC BY 4.0Reference data
a (3R)-3-hydroxyacyl-CoAa (2E)-enoyl-CoA+water
Catalysed by HSD17B4
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:26526CC BY 4.0Reference data
a (3R)-3-hydroxyacyl-CoA+NAD(1-)a 3-oxoacyl-CoA+NADH(2-)+hydron
Catalysed by HSD17B4 or HSD17B8
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32711CC BY 4.0Reference data
a (3R)-3-hydroxyacyl-CoAa (3S)-3-hydroxyacyl-CoA
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:34083CC BY 4.0Reference data
[(R)-3-hydroxyalkanoate](n)+a (3R)-3-hydroxyacyl-CoA[(R)-3-hydroxyalkanoate](n+1)+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:66924CC BY 4.0Reference data
Other names
1 name
Resolves to: a (3R)-3-hydroxyacyl-CoA
- Also called
- (3R)-hydroxy fatty acyl-CoAs