a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine

Three steps

• CHEBI:16436Reach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. ceramide:phosphatidylcholine cholinephosphotransferase
  3. ceramide cholinephosphotransferase (CDP-choline)

  Catalysed by GBA1, GALC, GBA3, GBA2 and 2 moreGolgi apparatus, endoplasmic reticulum

• pregnenoloneReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
  3. 6 reduced [adrenodoxin] + cholesterol + 3 O2 + 6 H(+) = 4-methylpentanal + pregnenolone + 6 oxidized [adrenodoxin] + 4 H2O

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 more

• quinolinic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. Transport of Quinolinic Acid

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 1 morelysosome, extracellular space, cytosolOne of 2 routes

• psychosineReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 4 moreGolgi apparatus, cytosol

• 1-acyl-sn-glycerol 3-phosphateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 8 moreGolgi apparatus, mitochondrial matrix

• oxalic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. transport of oxalate and sulfate (cytosol to extracellular)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 1 morelysosome, extracellular space, cytosol

• a cholesterol esterReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. an acyl-CoA + cholesterol = a cholesterol ester + CoA

  Catalysed by GBA1, GALC, GBA3, GBA2 and 6 moreGolgi apparatusOne of 2 routes

• aldehydo-N-acetyl-D-mannosamineReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)
  2. Acylneuraminyl hydrolase
  3. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

  Catalysed by ST3GAL5, NEU4, NEU1, NEU3 and 2 morelysosome, cytosol

• linoleic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• sulfiteReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• a 2-acylglycerolReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. ceramide:phosphatidylcholine cholinephosphotransferase
  3. a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)

  Catalysed by GBA1, GALC, GBA3, GBA2 and 5 moreGolgi apparatus

• a monoacylglycerolReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. ceramide:phosphatidylcholine cholinephosphotransferase
  3. 1,2-diacyl-sn-glycerol acylhydrolase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 17 moreGolgi apparatus, extracellular spaceOne of 9 routes

• 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. Acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 8 moreGolgi apparatus, cytosol

• cholesteryl 3-beta-D-glucosideReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
  3. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 moreOne of 8 routes

• 7alpha-hydroxycholesterolReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
  3. cholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 7alpha-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 more

• 3,3'-diiodo-L-thyronine sulfateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. Steryl-Sulfatase

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 1 morelysosome, Golgi apparatusOne of 2 routes

• 26-hydroxycholesterolReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
  3. cholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 26-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 more

• a triacylglycerolReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 9 moreGolgi apparatus, cytosolOne of 2 routes

• a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. UDP-glucose:N-acylsphingosine D-glucosyltransferase
  3. glucosylceramide pool to LacCer pool conversion

  Catalysed by GBA1, GALC, GBA3, GBA2 and 36 morecytosol, endoplasmic reticulumOne of 5 routes

• 4-methylpentanalReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
  3. 6 reduced [adrenodoxin] + cholesterol + 3 O2 + 6 H(+) = 4-methylpentanal + pregnenolone + 6 oxidized [adrenodoxin] + 4 H2O

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 more

• fumaric acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. transport of fumarate and sulfate (cytosol to mitochondria)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 1 morelysosome, mitochondrial matrix, cytosolOne of 2 routes

• CHEBI:18132Reach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. ceramide:phosphatidylcholine cholinephosphotransferase
  3. Sphingomyelin cholinephosphohydrolase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 7 moreGolgi apparatus, cytosolOne of 4 routes

• dodecanoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• cholesteryl 3-beta-D-xylosideReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
  3. a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-xyloside + an N-acylsphing-4-enine

  Catalysed by GBA1, GALC, GBA3, GBA2One of 3 routes

• (11Z)-docosenoyl-CoA(4-)Reach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. acyl-CoA pool formation and breakdown

  Catalysed by GBA1, GALC, GBA3, GBA2 and 4 moreGolgi apparatus, cytosol

• (7Z)-tetradecenoyl-CoAReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. acyl-CoA pool formation and breakdown

  Catalysed by GBA1, GALC, GBA3, GBA2 and 4 moreGolgi apparatus, cytosol

• docosanoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• octadecanoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• alpha-linolenic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• folic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. Folate Transport by Oats

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, extracellular space, cytosolOne of 2 routes

• elaidic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. acyl-CoA:sphingosine N-acyltransferase
  3. acyl-CoA pool formation and breakdown

  Catalysed by GBA1, GALC, GBA3, GBA2 and 4 moreGolgi apparatus, cytosolOne of 13 routes

• alpha-D-galactoseReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. galactitol + NADP(+) = D-galactose + NADPH + H(+)
  3. galactitol:NADP+ 1-oxidoreductase

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morecytosolOne of 2 routes

• all-cis-docosa-4,7,10,13,16,19-hexaenoic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• a dicarboxylateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• N-glycoloylneuraminateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)
  2. Acylneuraminyl hydrolase
  3. CMP-N-acetylneuraminate monooxygenase (N-acetylneuraminate)

  Catalysed by ST3GAL5, NEU4, NEU1, NEU3 and 1 morelysosome, cytosol

• chlorine(.)Reach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. transport of chloride and sulfate (cytosol to extracellular)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 1 morelysosome, extracellular space, cytosol

• phosphocholineReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. ceramide:phosphatidylcholine cholinephosphotransferase
  3. a sphingomyelin + H2O = phosphocholine + an N-acylsphing-4-enine + H(+)

  Catalysed by GBA1, GALC, GBA3, GBA2 and 7 moreGolgi apparatus

• D-aspartateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. D-aspartate(in) + sulfate(out) = D-aspartate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• L-aspartateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• oxalateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 5 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• maleateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. maleate(in) + sulfate(out) = maleate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• malonic acidReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. transport of malonate and sulfate (cytosol to mitochondria)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 1 morelysosome, mitochondrial matrix, cytosolOne of 2 routes

• tetradecanoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• (9Z)-octadecenoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• (2R,3R)-tartrateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. (2R,3R)-tartrate(in) + sulfate(out) = (2R,3R)-tartrate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• (S,S)-tartrateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. (S,S)-tartrate(in) + sulfate(out) = (S,S)-tartrate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• (3R)-citramalateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. (3R)-citramalate(in) + sulfate(out) = (3R)-citramalate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• (3S)-citramalateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
  2. Sulfatide sulfohydrolase
  3. (3S)-citramalate(in) + sulfate(out) = (3S)-citramalate(out) + sulfate(in)

  Catalysed by GAL3ST1, ARSA, ARSD, ARSL and 2 morelysosome, inner side of the membrane, outer side of the membraneOne of 2 routes

• hexacosanoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes

• tetracosanoateReach from here →
  1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
  2. N-Acylsphingosine amidohydrolase
  3. (10Z)-heptadecenoic acid formation

  Catalysed by GBA1, GALC, GBA3, GBA2 and 1 morelysosome, extracellular spaceOne of 12 routes