1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

235 compounds within 3 steps: 6 in 1, 24 in 2, 205 in 3

Three steps

(9Z,12Z)-octadecadienoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 6 morecytosolOne of 2 routes
octanoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. Beta Oxidation Fatty Acid
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 7 morecytosol, mitochondrial matrix
octadecanoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 7 more
1-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. sn-glycerol 3-phosphate + hexadecanoyl-CoA = 1-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 more
O-acetyl-(R)-carnitineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. Acetyl-CoA:carnitine O-acetyltransferase
Catalysed by PNPLA2, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 9 routes
sphing-4-enineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. N-hexadecanoylsphing-4-enine + H2O = sphing-4-enine + hexadecanoate
3. H2O[c] + N-hexadecanoylsphing-4-enine[c] = palmitate[c] + sphingosine[c]
Catalysed by PNPLA2, NAAA, ASAH1, ACER2 and 1 morenucleus, cytosolOne of 5 routes
sphinganine 1-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
3. Sphinganine-1-phosphate pamlmitaldehyde-lyase
Catalysed by PNPLA2, ALDH3B1, ALDH3B2, ALDH3A2 and 1 morecytosol
L-phenylalanineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O
3. L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O
Catalysed by PNPLA2, PM20D1
a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 6 more
3-oxosphinganineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 more
1-hexadecanoylglycerone 3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. dihydroxyacetone phosphate + hexadecanoyl-CoA = 1-hexadecanoylglycerone 3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
an acyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. acyl-CoA pool formation and breakdown
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 5 morecytosol
sn-glycero-3-phospho-1D-myo-inositolReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
Catalysed by PNPLA2, ABHD12
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNPLA2cytosol, extracellular spaceOne of 12 routes
(2E)-hexadecenoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 moreOne of 2 routes
(9Z)-hexadecenoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 10 more
sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
Catalysed by PNPLA2, ABHD12One of 2 routes
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 10 moreOne of 2 routes
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. a 1-acyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
N-hexadecanoyl-(4R)-hydroxysphinganineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. (4R)-hydroxysphinganine + hexadecanoyl-CoA = N-hexadecanoyl-(4R)-hydroxysphinganine + CoA + H(+)
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 10 more
N-hexadecanoylsphinganineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. sphinganine + hexadecanoyl-CoA = N-hexadecanoylsphinganine + CoA + H(+)
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 more
all-trans-retinyl 9Z-octadecenoateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol
Catalysed by PNPLA2, DGAT1, DGAT2, PNPLA4
3-oxooctadecanoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctadecanoyl-CoA + CO2 + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 more
(8Z,11Z,14Z)-eicosatrienoateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNPLA2cytosol, extracellular spaceOne of 13 routes
1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 more
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 moreOne of 2 routes
1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoate + H(+)
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoate + H(+)
Catalysed by PNPLA2, ABHD16A
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 7 more
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 7 more
1,2-dihexadecanoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
N-(hexadecanoyl)-sphing-4-enine-1-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. N-hexadecanoylsphing-4-enine + H2O = sphing-4-enine + hexadecanoate
3. N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by PNPLA2, NAAA, ASAH1, ACER2 and 2 more
1,2-dihexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 11 more
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 moreOne of 2 routes
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 moreOne of 2 routes
(9Z)-octadecen-1-olReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-octadecenoyl-CoA + 2 NADPH + 2 H(+) = (9Z)-octadecen-1-ol + 2 NADP(+) + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 6 more
3-oxo-(11Z)-eicosenoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-eicosenoyl-CoA + CO2 + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 9 more
N-(9Z-octadecenoyl)-sphinganineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. sphinganine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-sphinganine + CoA + H(+)
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 7 more
2-hydroxyhexadecanoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexadecanoyl-CoA + succinate + CO2
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
(6Z)-hexadecenoyl-CoAReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 9 more
N-acetylcysteamineReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)
3. S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)
Catalysed by PNPLA2, PPT1, PPT2
1-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 8 more
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 15 moreOne of 2 routes
1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 6 more
1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 9 more
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + hexadecanoate + H(+)
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL4, ACSL3 and 15 more
1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-heptadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by PNPLA2, SLC27A2, ACSL3, ACSL1 and 7 more