N-eicosanoyl-sphing-4-enine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

132 compounds within 3 steps: 2 in 1, 17 in 2, 113 in 3

Three steps

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 3 routes
a fatty acidReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid
Catalysed by ACER2, CERS1, CERS6, CERS3 and 8 more
phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)
Catalysed by ACER2, PAFAH2, SMPD2
acetateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
Catalysed by ACER2, PAFAH2, ASAH1
tetradecanoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 13 routes
(9Z)-octadecenoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 14 routes
hexacosanoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 12 routes
tetracosanoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 13 routes
an N-acylsphinganineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. N-acylsphingosine amidohydrolase
Catalysed by ACER2, ASAH1, ACER1, ASAH2 and 1 morecytosol
(9Z)-hexadecenoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 12 routes
(15Z)-tetracosenoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 13 routes
(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 12 routes
(11Z)-eicosenoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 12 routes
1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACER2, PAFAH2, LPCAT4
1-O-hexadecyl-sn-glycerolReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)
Catalysed by ACER2, PAFAH2, SMPD2
1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACER2, PAFAH2, LPCAT2, LPCAT1
1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACER2, PAFAH2, LPCAT4One of 2 routes
octadecanoyl-CoAReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. Beta Oxidation of Long Chain Fatty Acid
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 7 morecytosol, mitochondrial matrixOne of 2 routes
an N-acylsphing-4-enine 1-phosphateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)
Catalysed by ACER2, CERS1, CERS6, CERS3 and 5 more
a 2-acyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15
a 1-acyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15
phosphoethanolamineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. sphing-4-enine + ATP = sphing-4-enine 1-phosphate + ADP + H(+)
3. sphing-4-enine 1-phosphate = (2E)-hexadecenal + phosphoethanolamine
Catalysed by ACER2, SPHK2, SPHK1, SGPL1
an acyl-CoAReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. acyl-CoA pool formation and breakdown
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 3 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 12 routes
a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine
Catalysed by ACER2, PAFAH2, PLA2G15
a 1-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by ACER2, PAFAH2, PLA2G15
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by ACER2, PAFAH2, PLA2G15
a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by ACER2, PAFAH2, PLA2G15
a 2-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by ACER2, PAFAH2, PLA2G15
N-eicosanoylsphinganineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + sphinganine = N-eicosanoylsphinganine + CoA + H(+)
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 8 morecytosol
CHEBI:67119Reach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
3. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
Catalysed by ACER2cytosol
3-oxodocosanoyl-CoAReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. very-long-chain 3-oxoacyl-CoA synthase (eicosanoyl-CoA)
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 12 morecytosolOne of 3 routes
(8Z,11Z,14Z)-eicosatrienoateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by ACER2cytosol, extracellular spaceOne of 12 routes
1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACER2, PAFAH2, LPCAT1One of 3 routes
1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by ACER2, PAFAH2, PLA2G15
N-(hexadecanoyl)-sphing-4-enine-1-phosphateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. sphing-4-enine + hexadecanoyl-CoA = N-hexadecanoylsphing-4-enine + CoA + H(+)
3. N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by ACER2, CERS6, TLCD3B, CERS5 and 2 more
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 4 routes
1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by ACER2, PAFAH2, PLA2G15One of 3 routes
an N-acylsphing-4-enine 1-phosphoethanolamineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
3. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by ACER2, CERS1, CERS6, CERS3 and 6 more
1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine
3. 1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-galactoside + N-dodecanoylsphing-4-enine
Catalysed by ACER2, NAAA, ASAH1, ASAH2 and 2 more
1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 3 routes
(2E)-eicosenoyl-CoAReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. acyl-CoA oxidase (eicosanoyl-CoA)
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 7 morecytosol, peroxisomeOne of 4 routes
1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine = 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G4C
eicosan-1-olReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
Catalysed by ACER2, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 8 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 2 routes
1-octadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 5 routes
2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by ACER2, PAFAH2, PLA2G15
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine
2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by ACER2, PAFAH2, PLA2G15One of 9 routes