1,2-di-(9Z-octadecenoyl)-sn-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

263 compounds within 3 steps: 10 in 1, 59 in 2, 194 in 3

Three steps

O-octanoyl-(R)-carnitineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. solute carrier (L-carnitine)
Catalysed by LIPC, DAGLB, DAGLA, SLC25A20endoplasmic reticulum, cytosol, mitochondrial matrixOne of 7 routes
dodecanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)
Catalysed by LIPC, DAGLB, DAGLA, ASAH1 and 5 more
9-(9Z,12Z-octadecadienoyloxy)-octadecanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 9-hydroxy-octadecanoate + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 9-(9Z-octadecenoyloxy)-octadecanoate + 2-(9Z-octadecenoyl)-glycerol
3. 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol + 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate
Catalysed by LIPC, DAGLB, DAGLA, PNPLA2
9-(10Z-heptadecenoyloxy)-octadecanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 9-hydroxy-octadecanoate + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 9-(9Z-octadecenoyloxy)-octadecanoate + 2-(9Z-octadecenoyl)-glycerol
3. 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(10Z-heptadecenoyl)-sn-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate
Catalysed by LIPC, DAGLB, DAGLA, PNPLA2
1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 3-octadecanoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
1-octanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-octanoylglycerol + (9Z)-octadecenoyl-CoA = 1-octanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
1-dodecanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-dodecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-dodecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 9 more
1-octadecanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-octadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 9 more
1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 9 more
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-tetradecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 13 more
1-decanoyl-3-(9Z-octadecenoyl)-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-decanoylglycerol + (9Z)-octadecenoyl-CoA = 1-decanoyl-3-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
2,3-di-(10Z-heptadecenoyl)-sn-glycerolReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 9-hydroxy-octadecanoate + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 9-(9Z-octadecenoyloxy)-octadecanoate + 2-(9Z-octadecenoyl)-glycerol
3. 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(10Z-heptadecenoyl)-sn-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate
Catalysed by LIPC, DAGLB, DAGLA, PNPLA2
1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol)Reach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
3. 2 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by LIPC, DAGLB, DAGLA, ABHD12 and 1 more
docosanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
octadecanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 13 routes
N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →
1. CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
3. N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)
Catalysed by CEPT1, PLAAT5, NAPEPLD
alpha-linolenic acidReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 13 routes
L-glyceraldehydeReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 2-(9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
3. glycerol + NADP(+) = L-glyceraldehyde + NADPH + H(+)
Catalysed by LIPC, DAGLB, DAGLA, ABHD16A and 8 more
elaidic acidReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 13 routes
all-cis-docosa-4,7,10,13,16,19-hexaenoic acidReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
chlorine(.)Reach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. Carnitine Transport by Atb0
Catalysed by LIPC, DAGLB, DAGLA, SLC6A14endoplasmic reticulum, cytosol, extracellular space
phosphocholineReach from here →
1. CDP-choline + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)
2. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+)
Catalysed by CEPT1, PLA2G15, ENPP6, ABHD12One of 2 routes
tetradecanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
a 1-O-alkyl-sn-glycero-3-phosphocholineReach from here →
1. CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
3. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
Catalysed by CEPT1, PLAAT5, PLAAT2, LCAT
hexacosanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
tetracosanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
an N-acylsphinganineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. N-acylsphingosine amidohydrolase
Catalysed by LIPC, DAGLB, DAGLA, ASAH1 and 4 morecytosol
eicosanoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
(9Z)-hexadecenoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 18 routes
(15Z)-tetracosenoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 15 routes
(11Z)-eicosenoateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by LIPC, DAGLB, DAGLAcytosol, extracellular spaceOne of 12 routes
1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
cholesteryl (9Z-octadecenoate)Reach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 9 morecytosol, endoplasmic reticulumOne of 3 routes
butanoyl-CoAReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. transport of butyryl-CoA and L-carnitine (cytosol to mitochondria)
Catalysed by LIPC, DAGLB, DAGLA, SLC33A1 and 2 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes
hexadecanoyl-CoAReach from here →
1. CDP-choline + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)
2. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by CEPT1, TAFAZZIN, LPGAT1
(9Z,12Z)-octadecadienoyl-CoAReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 morecytosolOne of 2 routes
octanoyl-CoAReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. Beta Oxidation Fatty Acid
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 9 morecytosol, mitochondrial matrix
octadecanoyl-CoAReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 9 more
1-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
3. 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + choline + H(+)
Catalysed by CEPT1, PLAAT5, PLAAT2, ENPP2 and 2 more
O-acetyl-(R)-carnitineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. Acetyl-CoA:carnitine O-acetyltransferase
Catalysed by LIPC, DAGLB, DAGLA, CPT1A and 2 moreendoplasmic reticulum, cytosolOne of 9 routes
sn-glycerol 3-phosphateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 2-(9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
3. glycerol + ATP = sn-glycerol 3-phosphate + ADP + H(+)
Catalysed by LIPC, DAGLB, DAGLA, ABHD16A and 10 moreOne of 2 routes
sn-glycerol 1-phosphateReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. 2-(9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
3. sn-glycerol 1-phosphate + H2O = glycerol + phosphate
Catalysed by LIPC, DAGLB, DAGLA, ABHD16A and 7 more
sphing-4-enineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
3. H2O[r] + N-(9Z-octadecenoyl)-sphing-4-enine[r] = oleate[r] + sphingosine[r]
Catalysed by LIPC, DAGLB, DAGLA, ASAH1 and 4 moreendoplasmic reticulumOne of 3 routes
L-phenylalanineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O
3. L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O
Catalysed by LIPC, DAGLB, DAGLA, PM20D1
a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 8 more
an acyl-CoAReach from here →
1. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. acyl-CoA pool formation and breakdown
Catalysed by LIPC, DAGLB, DAGLA, SLC27A2 and 7 morecytosol