N-(9Z-octadecenoyl)-L-leucine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

452 compounds within 3 steps: 2 in 1, 41 in 2, 409 in 3

Three steps

hexadecyl (9Z)-octadecenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. hexadecan-1-ol + (9Z)-octadecenoyl-CoA = hexadecyl (9Z)-octadecenoate + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 7 more
1-O-(9Z)-hexadecenyl (9Z)-octadecenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 7 more
octadecyl (9Z)-octadecenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. octadecan-1-ol + (9Z)-octadecenoyl-CoA = octadecyl (9Z)-octadecenoate + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 7 more
1-O-(9Z)-octadecenyl (9Z)-octadecenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 7 more
1-O-eicosanyl (9Z)-octadecenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. eicosan-1-ol + (9Z)-octadecenoyl-CoA = 1-O-eicosanyl (9Z)-octadecenoate + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
1,3-di-(9Z-octadecenoyl)-glycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 7 moreOne of 2 routes
2,3-di-(9Z)-octadecenoyl-sn-glycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
Catalysed by PM20D1, DGAT1, LIPA, PNPLA4 and 3 moreOne of 2 routes
1-(9Z-octadecenoyl)-3-hexadecanoylglycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 7 more
di-(9Z)-octadecenoylglycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = di-(9Z)-octadecenoylglycerol + (9Z)-octadecenoate + H(+)
Catalysed by PM20D1, DGAT1, LIPA, PNPLA4 and 10 moreOne of 2 routes
1-O-hexadecyl-3-(9Z)-octadecenoylglycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-O-hexadecylglycerol + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
dodecanedioyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Activation of dodecanedioic acid
Catalysed by PM20D1mitochondrial matrix, cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Production of Sebacoylcarnitine
Catalysed by PM20D1, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Production of Suberylcarnitine
Catalysed by PM20D1, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by PM20D1mitochondrial matrix, cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by PM20D1, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by PM20D1, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by PM20D1, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by PM20D1, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 5 routes
1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PM20D1, ABHD12, LPGAT1
4,8-dimethylnonanoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by PM20D1, CRAT, CROTmitochondrial matrix, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by PM20D1, ACAA1, HSD17B4, EHHADH and 1 moremitochondrial matrix, peroxisome
hexadecanedioyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Production of Hexadecanedioylcarnitine
Catalysed by PM20D1, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 2 routes
O-dodecanoyl-R-carnitineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Utilized Transport
3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by PM20D1, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 7 routes
(11Z,14Z)-eicosadienoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PM20D1cytosol, extracellular spaceOne of 12 routes
(17Z)-hexacosenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PM20D1cytosol, extracellular spaceOne of 12 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PM20D1cytosol, extracellular spaceOne of 12 routes
(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PM20D1cytosol, extracellular spaceOne of 12 routes
pristanoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. fatty-acid-CoA ligase
Catalysed by PM20D1, SLC27A2mitochondrial matrix, cytosolOne of 2 routes
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 8 more
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
undecanoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by PM20D1, ACSM4, ACSM1, ACSM2A and 3 moremitochondrial matrix, cytosolOne of 3 routes
(2E,9Z)-octadecadienoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. long-chain-fatty-acid-CoA ligase (oleate)
3. medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by PM20D1, SLC27A2, ACSL4, ACSL3 and 9 morecytosol, mitochondrial matrixOne of 4 routes
(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PM20D1cytosol, extracellular spaceOne of 12 routes
1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA
Catalysed by PM20D1, ABHD12, AGPAT3, AGPAT5
tricosanoateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PM20D1cytosol, extracellular spaceOne of 12 routes
thio-Mo-molybdopterinReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of cysteine and leucine (cytosol to extracellular)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by PM20D1, SLC7A9, SLC3A1, MOCOSextracellular space, cytosol
glycodeoxycholateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of glycine and leucine (cytosol to extracellular)
3. Glycodeoxycholate amidohydrolase
Catalysed by PM20D1, SLC7A5extracellular space, cytosolOne of 2 routes
1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
(5Z)-tetradecenoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by PM20D1, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 8 routes
O-(9Z)-octadecenoyl-(R)-carnitineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (R)-carnitine + (9Z)-octadecenoyl-CoA = O-(9Z)-octadecenoyl-(R)-carnitine + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Utilized Transport
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by PM20D1, CRAT, CROTendoplasmic reticulum, cytosol, peroxisomeOne of 5 routes
(3E)-decenoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by PM20D1, ACADM, ECHS1, ACAA2 and 1 moremitochondrial matrix
1-decanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-decanoylglycerol + (9Z)-octadecenoyl-CoA = 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by PM20D1, SLC27A2, ACSL3, ACSL1 and 6 more
N-tetradecanoylglycineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of glycine and leucine (cytosol to extracellular)
3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by PM20D1, SLC7A5, GLYATL2extracellular space, cytosol
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. Acetylation of Leucine
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by PM20D1, HADHA, ACAA2, HADHBmitochondrial matrix
N-eicosanoylglycinateReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of glycine and leucine (cytosol to extracellular)
3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by PM20D1, SLC7A5, BAATextracellular space, cytosol
N-docosanoylglycineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of glycine and leucine (cytosol to extracellular)
3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by PM20D1, SLC7A5, BAATextracellular space, cytosol
N-hexacosanoylglycineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of glycine and leucine (cytosol to extracellular)
3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by PM20D1, SLC7A5, BAATextracellular space, cytosol
an N(2)-acyl-L-glutamineReach from here →
1. N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
2. transport of glutamine and leucine (cytosol to extracellular)
3. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by PM20D1, SLC7A5, GLYATL1B, GLYATL1extracellular space, cytosol