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Proteins/UNIPROT:Q9UBM8
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity)..
Function from UniProtKB (Q9UBM8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
23 statements
23 statements · 6 reference databases · Subject: MGAT4C · Sources: Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
4 reactions
MAM02507g+CHEBI:16264MAM01868g+proton+UDP
Catalysed by MGAT4A or MGAT4B or MGAT4C
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.145Golgi apparatus
Human-GEM MAR07327CC BY 4.0Reference data
MAM01869g+CHEBI:16264MAM01870g+proton+UDP
Catalysed by MGAT4C
7 names
Resolves to: MGAT4C
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.201Golgi apparatus
Human-GEM MAR07329CC BY 4.0Reference data
MAM02507g+CHEBI:16264proton+MAM02512g+UDP
Catalysed by MGAT4A or MGAT4B or MGAT4C
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.145Golgi apparatus
Human-GEM MAR08693CC BY 4.0Reference data
N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+UDP-N-acetyl-alpha-D-glucosamineN(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+UDP+hydron
Catalysed by MGAT4C or MGAT4A or MGAT4B
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:16057CC BY 4.0Reference data