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Proteins/UNIPROT:Q9UBQ6
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains..
Function from UniProtKB (Q9UBQ6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
20 statements
20 statements · 6 reference databases · Subject: EXTL2 · Sources: Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
2 reactions
MAM00762g+CHEBI:16264proton+MAM02081g+UDP
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.223Golgi apparatus
Human-GEM MAR07207CC BY 4.0Reference data
3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein]+UDP-N-acetyl-alpha-D-glucosamine3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein]+UDP+
6 names
Resolves to: EXTL2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16221CC BY 4.0Reference data