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Proteins/UNIPROT:Q92935
Glycosyltransferase required for the biosynthesis of heparan-sulfate (HS). Transfers N-acetyl-alpha-D-glucosamine to the nascent HS chain (GlcNAcT-II activity). Appears to lack GlcNAcT I and GlcAT-II activities..
Function from UniProtKB (Q92935), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
15 statements
15 statements · 5 reference databases · Subject: EXTL1 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
5 reactions
MAM02088g+CHEBI:16264proton+MAM02089g+UDP
Catalysed by EXT1 & EXT2 or EXTL3 or EXTL1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.223, 2.4.1.224, 2.4.1.225Golgi apparatus
Human-GEM MAR07209CC BY 4.0Reference data
MAM02090g+CHEBI:16264proton+MAM02091g+UDP
Catalysed by
4 names
Resolves to: EXTL1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.223, 2.4.1.224, 2.4.1.225Golgi apparatus
Human-GEM MAR07211CC BY 4.0Reference data
MAM02092g+CHEBI:16264proton+MAM02093g+UDP
Catalysed by EXT1 & EXT2 or EXTL3 or EXTL1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.223, 2.4.1.224, 2.4.1.225Golgi apparatus
Human-GEM MAR07213CC BY 4.0Reference data
MAM02094g+CHEBI:16264proton+MAM02095g+UDP
Catalysed by EXT1 & EXT2 or EXTL3 or EXTL1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.223, 2.4.1.224, 2.4.1.225Golgi apparatus
Human-GEM MAR07215CC BY 4.0Reference data
3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein]+UDP-N-acetyl-alpha-D-glucosamine3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein]+UDP+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:16213CC BY 4.0Reference data