Loading the page.
Proteins/UNIPROT:Q8NAT1
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity..
Function from UniProtKB (Q8NAT1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
10 statements
10 statements · 3 reference databases · Subject: POMGNT2 · Sources: Hetionet, Reactome, Rhea
1 reaction
3-O-(alpha-D-mannosyl)-L-threonyl-[protein]+UDP-N-acetyl-alpha-D-glucosamine3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein]+UDP+hydron
Catalysed by POMGNT2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:37663CC BY 4.0Reference data
6 names
Resolves to: POMGNT2