NCT00080483reporting_status×3, declared_contrast×1 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (1 The Effects of Testosterone Combined With G=unmatched, 2 The Effects of Testosterone Alone on Structural and Mechanic=unmatched)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00089843declared_contrast×2 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Actonel (Risedronate) 35 mg Weekly=unmatched, Testosterone=unmatched)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00114114declared_contrast×5 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Group 1: 0 g/Day=EXPERIMENTAL+subject, Group 2: 1.25 g/Day=EXPERIMENTAL+subject, Group 3: 2.5 g/Day=EXPERIMENTAL+subject, Group 4: 5 g/Day=EXPERIMENTAL+subject, Group 5: 10* g/Day=EXPERIMENTAL+suclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00194675declared_contrast×6 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Testosterone Gel + Oral Placebo=ACTIVE_COMPARATOR+subject, Testosterone Gel + Oral Dutasteride=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00729859declared_contrast×10 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Group 1: Acyline + Placebo Gel + Placebo Pill=unmatched, Group 2: Acyline + T-gel 10g/Day + Placebo Pill=unmatched, Group 3: Acyline + T-gel + Oral Anastrozole 1mg=unmatched)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00799617declared_contrast×16, stratified×14, outcome_node×7 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (AndroGel® (Testosterone Gel)=ACTIVE_COMPARATOR+subject, Placebo Gel=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00839319declared_contrast×4 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Acyline Plus Placebo=EXPERIMENTAL, Acyline Plus 15 IU hCG=EXPERIMENTAL, Acyline Plus 60 IU hCG=EXPERIMENTAL, Acyline Plus 125 IU hCG=EXPERIMENTAL, Acyline Plus Testosterone Gel=EXPERIMENTAL+subjeclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00957528declared_contrast×6 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Monthly Cycled Testosterone=EXPERIMENTAL+subject, Continuous Testosterone=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01121211declared_contrast×2 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Testosterone=ACTIVE_COMPARATOR+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01155518declared_contrast×1 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Testosterone=EXPERIMENTAL+subject, Clomiphene=EXPERIMENTAL, Placebo for Testosterone=PLACEBO_COMPARATOR, Placebo for Clomiphene=PLACEBO_COMPARATOR, Eugonadal Obese=NO_INTERVENTION, Normal Lean=unclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01215292declared_contrast×3 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Acyline + Testosterone Gel + Placebo=unmatched, Acyline + Tgel + Ketoconazole 400mg=unmatched, Acyline + Tgel + Ketoconazole 800mg=unmatched, Acyline & TGel & Dutasteride 2.5mg=unmatched, Acylineclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01327495declared_contrast×14 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Arm 1/Placebo Acyline Inject & Placebo Testosterone Gel=unmatched, Arm 2 Acyline Inject Every 2 Weeks & Daily T 1% Gel 1.25g=unmatched, Arm 3 Acyline Inject Every 2 Weeks & Daily T 1% Gel 2.5=unmclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01419236declared_contrast×9 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Testosterone Solution 2%=unmatched, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01446042declared_contrast×2 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (TBS-1 - b.i.d.=EXPERIMENTAL+subject, TBS-1 - b.i.d./t.i.d.=unmatched, TBS-1 - t.i.d.=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01585831declared_contrast×10 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Testosterone Gel 1%=EXPERIMENTAL+subject, Placebo Gel=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01595581declared_contrast×2, multiple_analyses×1 — 3 analyses of the same contrast (Wilcoxon (Mann-Whitney) p=0.35; Wilcoxon (Mann-Whitney) p=0.48; Wilcoxon (Mann-Whitney) p=0.74) -- the record does not declare which is primaryclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01686828declared_contrast×3 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Acyline & Placebo Gel & Placebo Pill=EXPERIMENTAL, Acyline & Testosterone Gel 1.25g/d & Placebo Pill=unmatched, Acyline & Testosterone Gel 5g/d & Placebo Pill=unmatched, Acyline & Testosterone Geclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01717768declared_contrast×4 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Part 1: 120 mg BID=EXPERIMENTAL+subject, Part 1: 240 mg BID=EXPERIMENTAL+subject, Part 2: 120 mg BID=EXPERIMENTAL+subject, Part 4 Cohort 1: 60 mg BID=unmatched, Part 4 Cohort 1: 60 mg TID=unmatchclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01816295declared_contrast×3, outcome_node×1, multiple_analyses×1 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Placebo Solution=PLACEBO_COMPARATOR, Testosterone Solution=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02222558declared_contrast×1 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Period 1: Single Dose=EXPERIMENTAL+subject, Period 2: Two Times Daily Dosing 90 mg=EXPERIMENTAL+subject, Period 3: Two Times Daily Dosing 120 mg=EXPERIMENTAL+subject, Period 3: Three Times Dailyclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02513940declared_contrast×5 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Testosterone=unmatched, Progesterone=unmatched, Placebo=unmatched)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02799277declared_contrast×3 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Drug=unmatched, Control=unmatched)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT03091348declared_contrast×10 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value ("SQ"=unmatched, "IM"=unmatched)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT06154200declared_contrast×2 — no posted analysis compares a testosterone arm with a placebo/no-intervention arm and carries a p-value (Vehicle Gel=PLACEBO_COMPARATOR, Testosterone Gel 4.5%=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=testosterone2026-09-29
Discarded — another reason, stated per paper23 papers
NCT00544440design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00586898design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00587431design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00645658design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00676676design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00695110design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00702650design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT00857454design×1 — allocation absent -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01136226design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01256671design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01415960design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01420861design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01464879design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT01893281design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02090114design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02149264design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02670343design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02777242design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT02995330design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT03123913design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT03203681design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
NCT04685993design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
PMID:41259548no claim extracted — cause not determined (one pass only) — measured: heart failure incidence, pooled hazard ratio from cohort studies of endogenous testosterone levelpipeline:batch2026-10-05
Discarded — an endpoint this vocabulary does not hold3 papers
NCT00304746declared_contrast×1, outcome_node×1 — "21-item Hamilton Depression Rating Scale Score (HAM-D)" names no outcome in the closed vocabularyclinicaltrials.gov intr search: query.intr=testosterone2026-09-29
PMID:41551464no claim extracted — vocabulary gap, passes disagreed: endpoint_near_miss / no_outcome_node — measured: composite endpoint of all-cause mortality OR liver transplant, pooled RR; the listed node covers pure all-cause mortality alone, not a composite that also counts liver transplant as an event | composite of all-cause mortality or liver transplant (LT), pooled as a risk ratio, in patients with advanced liver diseasepipeline:batch2026-09-29