(2E)-octadecenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

673 compounds within 3 steps: 3 in 1, 166 in 2, 504 in 3

Two steps

(9Z,12Z)-octadecadien-1-olReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 2 NADPH + 2 H(+) = (9Z,12Z)-octadecadien-1-ol + 2 NADP(+) + CoA
Catalysed by FADS2, FAR1cytosol
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoAReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA
Catalysed by FADS2, ELOVL7, ELOVL6, ELOVL3 and 1 morecytosol
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 4 routes
2-hydroxyoctadecanoyl-CoAReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. octadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctadecanoyl-CoA + succinate + CO2
Catalysed by TECRL, TECR, PHYHcytosol
(15Z)-tetracosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. glycerol-3-phosphate 1-O-acyltransferase (linoleoyl-CoA)
Catalysed by FADS2, GPAT3, GPAT2, GPAT4 and 1 morecytosolOne of 2 routes
1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphateReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by TECRL, TECR, GPAT3, LCLAT1 and 4 morecytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA
Catalysed by FADS2, AGPAT2, GPAT3, LPCAT2 and 3 morecytosol
1-octadecanoyl-sn-glycero-3-phosphateReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
Catalysed by TECRL, TECR, GPAT3, GPAT2 and 2 morecytosolOne of 2 routes
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by FADS2, LPCAT3cytosol
1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by FADS2, LPCAT3, MBOAT1cytosol
1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serine + CoA
Catalysed by TECRL, TECR, MBOAT1, LPGAT1cytosol
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, LPGAT1cytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by FADS2, LPCAT3cytosol
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by FADS2, LPCAT3cytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by TECRL, TECR, LPGAT1cytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECRL, TECR, LPGAT1cytosol
1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. a 1-acyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by FADS2, LPCAT3cytosol
1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by FADS2, LPCAT3cytosol
nonadecanoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by FADS2, LCLAT1cytosol
1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA = 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by TECRL, TECR, LCLAT1cytosol
1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by FADS2, LCLAT1cytosol
1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by TECRL, TECR, LPCAT4cytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by TECRL, TECR, MOGAT2, MOGAT1cytosol
1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by FADS2, MOGAT2, MOGAT1cytosol
hexadecyl octadecanoateReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by TECRL, TECR, AWAT1, AWAT2cytosol
dodecanedioyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Activation of dodecanedioic acid
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Production of Sebacoylcarnitine
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Production of Suberylcarnitine
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 2 routes
(13Z)-eicosenoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by CPT1A, CPT1C, CPT1B, CRAT and 1 morecytosol, peroxisomeOne of 3 routes