Compound
2-hydroxyoctadecanoyl-CoA
An acyl-CoA(4−) arising from deprotonation of the phosphate and diphosphate functions of 2-hydroxystearoyl-CoA.
Definition from ChEBI (CHEBI:74116), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C39H66N7O18P3S
- Mass
- 1045.977 g/mol
- Charge
- -4
- InChIKey
- OJQMIXCIJFLULT-WRPLWBMRSA-J
- SMILES
- CCCCCCCCCCCCCCCCC(O)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: 2-hydroxyoctadecanoyl-CoA · Sources: Rhea
- octadecanoyl-CoA is converted to 2-hydroxyoctadecanoyl-CoACompoundRhea RHEA:54624Inferred only
- 2-hydroxyoctadecanoyl-CoA is a substrate of CERS1ProteinRhea RHEA:36615Inferred only
- 2-hydroxyoctadecanoyl-CoA is a substrate of CERS3ProteinRhea RHEA:36615Inferred only
- 2-hydroxyoctadecanoyl-CoA is a substrate of HACL1ProteinRhea RHEA:55196Inferred only
- 2-hydroxyoctadecanoyl-CoA is a substrate of HACL2ProteinRhea RHEA:55196Inferred only
Reactions
3 reactions
2-hydroxyoctadecanoyl-CoA+sphinganineN-(2-hydroxyoctadecanoyl)-sphinganine+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:36615CC BY 4.0Reference data
octadecanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxyoctadecanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54624CC BY 4.0Reference data
2-hydroxyoctadecanoyl-CoACHEBI:138631+CHEBI:57376
Reaction pageLeft to rightBalanced
Rhea RHEA:55196CC BY 4.0Reference data
Other names
13 names
Resolves to: 2-hydroxyoctadecanoyl-CoA
- Also called
- 2-hydroxy-C18:0-CoA(4-)2-hydroxy-C18:0-CoA(4−)2-hydroxyoctadecanoyl-CoA(4-)2-hydroxyoctadecanoyl-CoA(4−)2-hydroxyoctadecanoyl-coenzyme A(4-)2-hydroxyoctadecanoyl-coenzyme A(4−)2-hydroxystearoyl-coenzyme A(4-)2-hydroxystearoyl-coenzyme A(4−)2-OH-C18:0-CoA(4-)2-OH-C18:0-CoA(4−)2-OH-stearoyl-CoA(4-)2-OH-stearoyl-CoA(4−)
- Systematic name
- 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-4-{[3-({2-[(2-hydroxyoctadecanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-2,2-dimethyl-4-oxobutyl] diphosphate}