sn-glycerol 3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

323 compounds within 3 steps: 8 in 1, 35 in 2, 280 in 3

Three steps

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 5 morecytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 6 moreOne of 2 routes
1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. pentadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 6 more
1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 5 more
1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)
3. 1-tetradecanoyl-sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 3 morecytosol
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
3. CDP-choline + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)
Catalysed by ENPP6, PCYT1A, PCYT1B, CEPT1
1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 2 more
a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphate + CoA
3. a 1-acyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT2 and 3 more
1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 7 more
1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 2 more
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (arachidonyl-CoA)
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 3 morecytosol
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + CDP-choline = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)
Catalysed by ENPP6, PCYT1A, PCYT1B, CHPT1 and 1 more
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ENPP6, PLA2G4A, LPCAT3One of 2 routes
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ENPP6, PLA2G4A, LPCAT3, LPCAT1
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ENPP6, PLA2G4A, MBOAT2
1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 2 more
1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 4 more
nonadecanoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by GPCPD1, CHAT, CPT1A, CPT1C and 1 morecytosolOne of 3 routes
1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 3 more
1-(9Z)-octadecenoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. (6Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 2 more
1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 2 more
1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ENPP6, PLA2G4A, LPCAT2
1-tetradecanoyl-sn-glycerolReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)
3. 1-tetradecanoyl-sn-glycerol 3-phosphate + H2O = 1-tetradecanoyl-sn-glycerol + phosphate
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
1-hexadecanoyl-sn-glycerolReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
3. 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
1-octadecanoyl-sn-glycerolReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ENPP6, PLA2G4A, MOGAT2, MOGAT1
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ENPP6, PLA2G4A, MOGAT2, MOGAT1
1-(9Z-octadecenoyl)-sn-glycerolReach from here →
1. sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate
Catalysed by GDPD5, GPCPD1, GPAT3, GPAT4 and 7 more
dodecanedioyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Activation of dodecanedioic acid
Catalysed by GPCPD1, CHATcytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Production of Sebacoylcarnitine
Catalysed by GPCPD1, CHAT, CPT1A, CPT1C and 1 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Production of Suberylcarnitine
Catalysed by GPCPD1, CHAT, CPT1A, CPT1C and 1 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by GPCPD1, CHATcytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by GPCPD1, CHAT, CPT1A, CPT1C and 1 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by GPCPD1, CHAT, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by GPCPD1, CHAT, CRAT, CROTcytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by GPCPD1, CHAT, ACAA1, HSD17B4 and 2 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Production of Hexadecanedioylcarnitine
Catalysed by GPCPD1, CHAT, CPT1A, CPT1C and 1 morecytosolOne of 2 routes
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPCPD1, GPAT3, GPAT2, GPAT4 and 2 morecytosol
pristanoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. fatty-acid-CoA ligase
Catalysed by GPCPD1, CHAT, SLC27A2cytosolOne of 2 routes
a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine
Catalysed by TMEM86A, TMEM86B
undecanoyl-CoAReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by GPCPD1, CHAT, ACSM4, ACSM1 and 4 morecytosolOne of 3 routes
(9S)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS1, PTGS2cytosol
(9R)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. sn-Glycero-3-phosphocholine glycerophosphohydrolase
2. choline + A = betaine aldehyde + AH2
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by GPCPD1, CHDH, PTGS1, PTGS2cytosol
1,2-didecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
3. 1,2-didecanoyl-sn-glycerol + CDP-choline = 1,2-didecanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
Catalysed by ENPP6, PCYT1A, PCYT1B, CEPT1
1,2-dioctanoyl-sn-glycero-3-phosphocholineReach from here →
1. sn-glycerol 3-phosphocholine + H2O = phosphocholine + glycerol + H(+)
2. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
3. 1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)
Catalysed by ENPP6, PCYT1A, PCYT1B, CHPT1 and 1 more