11-cis-retinol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

618 compounds within 3 steps: 11 in 1, 135 in 2, 472 in 3

Two steps

CHEBI:63544Reach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (adrenic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 7 routes
hexacosanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (cerotic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
tetracosanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 10 routes
docosanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 9 routes
all-trans-retinyl 9Z-octadecenoateReach from here →
1. all-trans-Retinol 11-cis-trans-isomerase
2. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol
Catalysed by PNPLA4, PNPLA2cytosol
(2E)-octadecenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Carnitine O-Palmitoyltransferase
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 8 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosolOne of 3 routes
di-(9Z)-octadecenoylglycerolReach from here →
1. all-trans-Retinol 11-cis-trans-isomerase
2. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol
Catalysed by PNPLA4, PNPLA2cytosol
2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. all-trans-Retinol 11-cis-trans-isomerase
2. all-trans-retinol + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by LRATcytosol
dodecanedioyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Activation of dodecanedioic acid
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 1 morecytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Production of Sebacoylcarnitine
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Production of Suberylcarnitine
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 1 morecytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 3 morecytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 5 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Production of Hexadecanedioylcarnitine
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. fatty-acid-CoA ligase
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 2 morecytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 7 morecytosolOne of 3 routes
9-cis-retinalReach from here →
1. 11-cis-retinol = 9-cis-retinol
2. Retinol Dehydrogenase (9-Cis, NADPH)
Catalysed by DEGS1, SDR16C5, RDH13, RDH11 and 3 morecytosolOne of 4 routes
hexadecanoateReach from here →
1. all-trans-retinyl hexadecanoate + H2O = 11-cis-retinol + hexadecanoate + H(+)
2. all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + hexadecanoate + H(+)
Catalysed by RPE65, PNLIP, PNPLA4, LIPEOne of 2 routes
(5Z)-tetradecenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 5 morecytosol, mitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 4 morecytosol, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. Palmitoyl-CoA:retinol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 9 morecytosolOne of 4 routes

Three steps

N(omega)-methyl-L-arginineReach from here →
Catalysed by DGAT1, LRAT, AWAT1, AWAT2 and 5 morecytosol, mitochondrial matrixOne of 2 routes
(5E)-tetradecenoyl-(R)-carnitineReach from here →