oleoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

757 compounds within 3 steps: 7 in 1, 189 in 2, 561 in 3

Three steps

1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
decyl (9Z)-octadecenoateReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. decan-1-ol + (9Z)-octadecenoyl-CoA = decyl (9Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
hexadecyl (9Z)-octadecenoateReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. hexadecan-1-ol + (9Z)-octadecenoyl-CoA = hexadecyl (9Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
1-O-(9Z)-hexadecenyl (9Z)-octadecenoateReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
octadecyl (9Z)-octadecenoateReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. octadecan-1-ol + (9Z)-octadecenoyl-CoA = octadecyl (9Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
1-O-(9Z)-octadecenyl (9Z)-octadecenoateReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
eicosan-1-olReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
1-O-eicosanyl (9Z)-octadecenoateReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. eicosan-1-ol + (9Z)-octadecenoyl-CoA = 1-O-eicosanyl (9Z)-octadecenoate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
hexadecyl (9Z)-hexadecenoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. hexadecan-1-ol + (9Z)-hexadecenoyl-CoA = hexadecyl (9Z)-hexadecenoate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
hexadecyl octadecanoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1,3-di-(9Z-octadecenoyl)-glycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosolOne of 2 routes
2,3-di-(9Z)-octadecenoyl-sn-glycerolReach from here →
1. Oleoyl-CoA hydrolase
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 7 morecytosolOne of 2 routes
1-(9Z-octadecenoyl)-3-hexadecanoylglycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
di-(9Z)-octadecenoylglycerolReach from here →
1. Oleoyl-CoA hydrolase
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = di-(9Z)-octadecenoylglycerol + (9Z)-octadecenoate + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 14 morecytosolOne of 2 routes
1-O-hexadecyl-3-(9Z)-octadecenoylglycerolReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-O-hexadecylglycerol + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosol
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosolOne of 3 routes
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosol
hexadecanedioateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Production of Hexadecanedioylcarnitine
3. hexadecanedioyl-CoA + H2O = hexadecanedioate + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, ABCD3cytosol
(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
3. ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol, endoplasmic reticulumOne of 2 routes
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acyl-CoA pool formation and breakdown
2. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)
Catalysed by LCLAT1, LPCAT1, GPAM, PLA2G15 and 1 morecytosolOne of 2 routes
3-oxo-(11Z)-octadecenoyl-CoAReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. (9Z)-hexadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
3-oxo-(13Z)-eicosenoyl-CoAReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA
Catalysed by CPT1A, CPT1C, CPT1B, ELOVL5cytosol
1-O-alkyl-2,3-diacyl-sn-glycerolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLA2G15cytosolOne of 2 routes
(25R)-cholest-5-ene-3beta,26-diolReach from here →
1. Acyl-CoA:cholesterol O-acyltransferase
2. Steryl-ester acylhydrolase
3. cholesterol,NADPH:oxygen oxidoreductase (5alpha,6alpha-epoxidizing)
Catalysed by SOAT2, SOAT1, CEL, LIPA and 1 moreendoplasmic reticulum, lysosome, mitochondrial matrixOne of 2 routes
1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
O-dodecanoyl-R-carnitineReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Carnitine O-Palmitoyltransferase
3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 11 routes
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
3. 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate
Catalysed by FADS2, AGPAT4, LPIN1cytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DHA)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphateReach from here →
1. Acyl-CoA:cholesterol O-acyltransferase
2. cholesteryl (9Z-octadecenoate) + H2O = cholesterol + (9Z)-octadecenoate + H(+)
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate(out) + cholesterol(in) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate(in) + cholesterol(out)
Catalysed by SOAT2, SOAT1, CEL, CES1 and 4 moreendoplasmic reticulum, inner side of the membrane, outer side of the membraneOne of 2 routes
(11Z,14Z)-eicosadienoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
3. (11Z,14Z)-eicosadienoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 10 morecytosolOne of 13 routes
(17Z)-hexacosenoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
3. Hexacosenoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosolOne of 13 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DPA)
3. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosolOne of 13 routes
(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (adrenic acid)
3. (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosolOne of 14 routes
2,6,10,14-tetramethylpentadecanoateReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. fatty-acid-CoA ligase
3. peroxisomal acyl-CoA thioesterase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 1 morecytosol, peroxisomeOne of 2 routes
a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPCAT2, LPCAT1cytosolOne of 2 routes
a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4cytosol
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 12 morecytosol
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosol
tetracosan-1-olReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. tetracosanoyl-CoA + 2 NADPH + 2 H(+) = tetracosan-1-ol + 2 NADP(+) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
(2E,9Z)-hexadecadienoyl-CoAReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. medium-chain acyl-CoA dehydrogenase (palmitoleoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 3 routes
trans-2-heptadecenoyl-CoAReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (margaric acid)
3. medium-chain acyl-CoA dehydrogenase (heptadecanoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 2 routes
(2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoAReach from here →
1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + O2 = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H2O2
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
(9S)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by FADS2, ACOT8, ACOT2, THEM5 and 3 morecytosol