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Reach

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

656 compounds within 3 steps: 5 in 1, 154 in 2, 497 in 3

Does it reach a compound?

Two steps

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by AGPAT4peroxisome
(5Z)-tetradecenoyl-CoAReach from here →
1. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 9 routes
(3E)-decenoyl-CoAReach from here →
1. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by BAAT, ACOT6, ACADM, ECHS1 and 2 morecytosol, mitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by BAAT, ACOT6, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrix
an N(2)-acyl-L-glutamineReach from here →
1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by GLYATL1B, GLYATL1cytosol
(7Z)-hexadecenoyl-CoAReach from here →
1. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 9 routes
tricosanoyl-CoAReach from here →
1. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
a 3-oxoacyl-CoAReach from here →
1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
Catalysed by ACAA1, SCP2, ACAA2, HADHBcytosol
13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoateReach from here →
1. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
2. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 = 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O
Catalysed by BAAT, ACOT6, PTGS2cytosol

Three steps

N(omega)-methyl-L-arginineReach from here →
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrixOne of 2 routes
(5E)-tetradecenoyl-(R)-carnitineReach from here →

Page 4 of 14

Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 7 routes

S-butanoyl-4'-phosphopantetheineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Butanoate:CoA ligase (AMP-forming)
butanoyl-CoA + H2O = S-butanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 7 morecytosol

S-octanoyl-4'-phosphopantetheineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Octanoyl-CoA:L-carnitine O-octanoyltransferase
octanoyl-CoA + H2O = S-octanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by BAAT, ACOT6, CROT, NUDT19 and 2 morecytosol, mitochondrial matrix

decanoyl-4'-phosphopantetheineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
medium-chain acyl-CoA ligase (decanoic acid)
decanoyl-CoA + H2O = decanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 5 morecytosol

S-dodecanoyl-4'-phosphopantetheineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (lauric acid)
dodecanoyl-CoA + H2O = S-dodecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol

tetradecanoyl-4'-phosphopantetheineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
tetradecanoyl-CoA + H2O = tetradecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol

21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
DHA[r] + O2[r] + FMNH2[r] = FMN[r] + H2O[r] + 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate[r]

Catalysed by BAAT, ACOT6, CYP2E1peroxisome, cytosol, endoplasmic reticulumOne of 3 routes

tauroursodeoxycholateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
bile acid-CoA:amino acid N-acyltransferase (taurodeoxycholate)
taurine to tauroursodeoxycholate conversion

Catalysed by BAAT, ACOT6cytosolOne of 2 routes

glycoursodeoxycholateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
glycine N-acyltransferase (N-arachidonoylglycine)
glycine to glycoursodeoxycholate conversion

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 1 morecytosol, mitochondrial matrixOne of 2 routes

leukotriene F4Reach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
N-acetyl-LTE4 to leukotriene E4 conversion
leukotriene F4 hydrolysis

Catalysed by BAAT, ACOT6, ZDHHC11B, NAA10 and 30 morecytosol

(17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate

Catalysed by BAAT, ACOT6, ALOX5, ALOX15peroxisome, cytosol

19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by BAAT, ACOT6, CYP4F8, CYP4F12peroxisome, cytosol

16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by BAAT, ACOT6, CYP4F8, CYP4F12peroxisome, cytosol

13,14-epoxy-(4Z,7Z,10Z,16Z,19Z)-docosapentaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13,14-epoxy-(4Z,7Z,10Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by BAAT, ACOT6, CYP4F8, CYP4F12peroxisome, cytosol

10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by BAAT, ACOT6, CYP4F8, CYP4F12peroxisome, cytosol

2,4-dinitrophenyl-S-glutathioneReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
N-acetyl-LTE4 to leukotriene E4 conversion
transport of leukotriene E4 (cytosol to extracellular)

Catalysed by BAAT, ACOT6, ZDHHC11B, NAA10 and 31 morecytosol, extracellular spaceOne of 2 routes

N-(9Z-octadecenoyl)glycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
glycine N-acyltransferase (N-arachidonoylglycine)
(9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix

N-octadecanoylglycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (stearate)
octadecanoyl-CoA + glycine = N-octadecanoylglycine + CoA + H(+)

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 2 routes

N-(9Z-hexadecenoyl)-glycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (palmitolate)
(9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes

(19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = (19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by BAAT, ACOT6, CYP1A1, CYP1A2 and 5 moreperoxisome, cytosol

(19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoateReach from here →

fatty acyl-CoA desaturase (N-C22:5CoA -> N-C22:6CoA)
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by BAAT, ACOT6, CYP1A1, CYP3A4 and 4 moreperoxisome, cytosol

2-hydroxyoctanoyl-CoAReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Octanoyl-CoA:L-carnitine O-octanoyltransferase
octanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctanoyl-CoA + succinate + CO2

Catalysed by BAAT, ACOT6, CROT, PHYHcytosol, mitochondrial matrix

2-hydroxydecanoyl-CoAReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
medium-chain acyl-CoA ligase (decanoic acid)
decanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydecanoyl-CoA + succinate + CO2

Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 5 morecytosol

2-hydroxyeicosanoyl-CoAReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (eicosanoate)
eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

2-hydroxydodecanoyl-CoAReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (lauric acid)
dodecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydodecanoyl-CoA + succinate + CO2

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

2-hydroxytetradecanoyl-CoAReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
tetradecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxytetradecanoyl-CoA + succinate + CO2

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

11-cis-retinyl tetradecanoateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes

9-cis-retinyl tetradecanoateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
9-cis-retinol + tetradecanoyl-CoA = 9-cis-retinyl tetradecanoate + CoA

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

13-cis-retinyl tetradecanoateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
13-cis-retinol + tetradecanoyl-CoA = 13-cis-retinyl tetradecanoate + CoA

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

all-trans-retinyl tetradecanoateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
all-trans-retinol + tetradecanoyl-CoA = all-trans-retinyl tetradecanoate + CoA

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

tetradecyl tetradecanoateReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (myristic acid)
tetradecan-1-ol + tetradecanoyl-CoA = tetradecyl tetradecanoate + CoA

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol

N-hexadecanoylglycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
glycine N-acyltransferase (N-arachidonoylglycine)
hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix

N-dodecanoylglycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
long-chain-fatty-acid-CoA ligase (lauric acid)
dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes

N-decanoylglycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
medium-chain acyl-CoA ligase (decanoic acid)
decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)

Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 5 morecytosolOne of 2 routes

N-octanoylglycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Octanoyl-CoA:L-carnitine O-octanoyltransferase
octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)

Catalysed by BAAT, ACOT6, CROT, GLYATL2cytosol, mitochondrial matrixOne of 2 routes

N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
glycine N-acyltransferase (N-arachidonoylglycine)
5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix

L-cystine-bis-glycineReach from here →

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
glycine N-acyltransferase (N-arachidonoylglycine)
L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 3 morecytosol, mitochondrial matrix

a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

acyl-CoA pool formation and breakdown
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol

a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

acyl-CoA pool formation and breakdown
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol

a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

acyl-CoA pool formation and breakdown
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol