octadecanoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

898 compounds within 3 steps: 43 in 1, 255 in 2, 600 in 3

Three steps

3-oxooctacosanyol-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (cerotic acid)
3. hexacosanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctacosanyol-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
3-oxotetracosanoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. very-long-chain 3-oxoacyl-CoA synthase (docosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 16 morecytosolOne of 3 routes
3-oxohexacosanoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. very-long-chain 3-oxoacyl-CoA synthase (malonyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 16 morecytosolOne of 3 routes
2-(9Z-octadecenoyl)-glycerolReach from here →
1. Stearoyl-CoA hydrolase
2. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 2 morecytosolOne of 4 routes
1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphateReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
3. 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA
Catalysed by SCD, HADHA, ACADVL, HADHB and 1 morecytosol, mitochondrial matrixOne of 2 routes
1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
3. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by SCD, HADHA, ACADVL, HADHB and 1 morecytosol, mitochondrial matrix
1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
3. (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, HADHA, ACADVL, HADHB and 2 morecytosol, mitochondrial matrixOne of 2 routes
(11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoAReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. (9Z,12Z)-octadecadienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA
Catalysed by SCD, FADS2, ELOVL7, ELOVL6 and 2 morecytosol
(11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (linolenate)
3. (9Z,12Z,15Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosol
3-oxo-(13Z)-docosenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
3. (11Z)-eicosenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-docosenoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
3-oxo-(15Z)-tetracosenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
3. (13Z)-docosenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(15Z)-tetracosenoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
N-(15Z-tetracosenoyl)-sphinganineReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (nervonic acid)
3. (15Z)-tetracosenoyl-CoA + sphinganine = N-(15Z-tetracosenoyl)-sphinganine + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosolOne of 2 routes
an N-tetracosenoylsphinganineReach from here →
1. sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)
2. N-(octadecanoyl)-sphinganine + H2O = sphinganine + octadecanoate
3. tetracosenoyl-CoA + sphinganine = an N-tetracosenoylsphinganine + CoA + H(+)
Catalysed by CERS1, CERS6, CERS3, CERS5 and 3 more
N-hexacosenoylsphinganineReach from here →
1. sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)
2. N-(octadecanoyl)-sphinganine + H2O = sphinganine + octadecanoate
3. hexacosenoyl-CoA + sphinganine = N-hexacosenoylsphinganine + CoA + H(+)
Catalysed by CERS1, CERS6, CERS3, CERS5 and 3 more
N-tetracosanoyl-heptadecasphing-4-enineReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. heptadecasphing-4-enine + tetracosanoyl-CoA = N-tetracosanoyl-heptadecasphing-4-enine + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
N-(2-hydroxytetracosenoyl)-sphinganineReach from here →
1. sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)
2. N-(octadecanoyl)-sphinganine + H2O = sphinganine + octadecanoate
3. 2-hydroxytetracosenoyl-CoA + sphinganine = N-(2-hydroxytetracosenoyl)-sphinganine + CoA + H(+)
Catalysed by CERS1, CERS6, CERS3, CERS5 and 3 more
(2E)-hexacosenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (cerotic acid)
3. acyl-CoA oxidase (hexacosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 2 routes
3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
3. (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
(2S)-2-aminobutanoateReach from here →
1. Stearoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 5 morecytosol, mitochondrial matrixOne of 2 routes
N-(15Z-tetracosenoyl)-sphing-4-enineReach from here →
1. Stearoyl-CoA hydrolase
2. acyl-CoA:sphingosine N-acyltransferase
3. N-(15Z-tetracosenoyl)-sphing-4-enine + H2O = (15Z)-tetracosenoate + sphing-4-enine
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 5 morecytosol, Golgi apparatusOne of 2 routes
N-(tetracosenoyl)-sphing-4-enineReach from here →
1. Stearoyl-CoA hydrolase
2. acyl-CoA:sphingosine N-acyltransferase
3. tetracosenoyl-CoA + sphing-4-enine = N-(tetracosenoyl)-sphing-4-enine + CoA + H(+)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 6 morecytosol, Golgi apparatus
1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. glycerol-3-phosphate 1-O-acyltransferase (linoleoyl-CoA)
Catalysed by SCD, FADS2, GPAT3, GPAT2 and 2 morecytosolOne of 3 routes
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, GPAT3, GPAT4 and 7 more
1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphateReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
3. heptadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 14 morecytosolOne of 2 routes
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, FADS2, AGPAT2, GPAT3 and 4 morecytosolOne of 3 routes
1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphateReach from here →
1. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. pentadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, GPAT3, GPAT4 and 6 more
1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 14 morecytosolOne of 2 routes
3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
3. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, FADS2, LPCAT3cytosol
(2E)-eicosenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. acyl-CoA oxidase (eicosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 4 routes
(2E)-docosenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. acyl-CoA oxidase (docosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 4 routes
(2E)-tetracosenoyl-CoAReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. acyl-CoA oxidase (tetracosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 3 routes
1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphateReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
3. (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by SCD, HADHA, ACADVL, HADHB and 1 morecytosol, mitochondrial matrixOne of 2 routes
1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by SCD, FADS2, LPCAT3, MBOAT1cytosol
1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-hexadecenoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by SCD, HADHA, ACADVL, HADHB and 1 morecytosol, mitochondrial matrix
1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphateReach from here →
1. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, GPAT3, GPAT4 and 7 more
1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosolOne of 2 routes
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. Stearoyl-CoA hydrolase
2. Arachidonate:CoA ligase (AMP-forming)
3. glycerol-3-phosphate 1-O-acyltransferase (arachidonyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosolOne of 2 routes
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosolOne of 2 routes
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by SCD, FADS2, LPCAT3cytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. dodecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosolOne of 2 routes
1-hexadecanoyl-sn-glycero-3-phospho-L-serineReach from here →
1. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)
Catalysed by SCD, SCD5, LPCAT4, LPCAT3 and 3 more
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPGAT1, PLA2G15, LPCAT3, LPCAT1
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by SCD, FADS2, LPCAT3cytosol
1-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. octadecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA
2. 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O = octadecanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine
Catalysed by LPCAT3, PLAAT3, PLA2G4C
1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. a 1-acyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by SCD, FADS2, LPCAT3cytosol
1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. stearoyl-CoA desaturase (N-C18:0CoA -> N-C18:1CoA)
2. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by SCD, FADS2, LPCAT3cytosol
1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphateReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosolOne of 2 routes
1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphateReach from here →
1. Stearoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
3. nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 12 morecytosolOne of 2 routes